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'''Unreleased structure'''


The entry 23iw is ON HOLD
==Cannabinoid Receptor 1-Gi Complex==
 
<StructureSection load='23iw' size='340' side='right'caption='[[23iw]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[23iw]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=23IW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=23IW FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1E5T:methyl+(2~{S},3~{R})-2-[[1-[(4-fluorophenyl)methyl]indazol-3-yl]carbonylamino]-3-oxidanyl-butanoate'>A1E5T</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=23iw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=23iw OCA], [https://pdbe.org/23iw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=23iw RCSB], [https://www.ebi.ac.uk/pdbsum/23iw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=23iw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNR1_HUMAN CNR1_HUMAN] Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.<ref>PMID:15620723</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Liao Y]]
[[Category: Zhang Y]]
Retrieved from "https://proteopedia.org/23iw"