28oa: Difference between revisions

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Created page with "'''Unreleased structure''' The entry 28oa is ON HOLD Authors: Description: Category: Unreleased Structures"
 
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'''Unreleased structure'''


The entry 28oa is ON HOLD
==Closed state Escherichia coli MscL mechanosensitive channel in DMPC nanodiscs==
 
<StructureSection load='28oa' size='340' side='right'caption='[[28oa]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[28oa]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=28OA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=28OA FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=28oa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=28oa OCA], [https://pdbe.org/28oa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=28oa RCSB], [https://www.ebi.ac.uk/pdbsum/28oa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=28oa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MSCL_ECOLI MSCL_ECOLI] Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition.<ref>PMID:10202137</ref> <ref>PMID:23416054</ref> <ref>PMID:23875651</ref> <ref>PMID:7511799</ref> <ref>PMID:9632260</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Hardman K]]
[[Category: Pliotas C]]
Retrieved from "https://proteopedia.org/28oa"