Nitric Oxide Synthase 3D structures: Difference between revisions

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* Endothelial NOS oxygenase domain (OD) 66-492
* Endothelial NOS oxygenase domain (OD) 66-492
**[[3nos]], [[4d1o]] – h-eNOS OD+ Arg - human
**[[3nos]], [[4d1o]] – h-eNOS OD+ Arg - human
**[[1m9j]] – h-eNOS OD+chlorzoxazone
**[[1m9j]] – h-eNOS OD+chlorzoxazone
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**[[1dm8]] – b-eNOS OD+triazole derivative
**[[1dm8]] – b-eNOS OD+triazole derivative
**[[1ed6]] – b-eNOS OD+NO
**[[1ed6]] – b-eNOS OD+NO
* Endothelial NOS heme domain
* Endothelial NOS heme domain
**[[6pou]], [[6pov]], [[6pow]], [[6pox]], [[6poy]], [[6poz]], [[6pp0]], [[6pp1]], [[6pp2]], [[6pp3]], [[6pp4]], [[7m56]], [[7tsg]], [[7tsh]], [[7tsi]], [[7tsk]], [[7tsl]], [[7tsm]], [[7tsn]], [[7tso]], [[7tsp]], [[7uao]], [[8fge]], [[8fgn]], [[8fgo]], [[8fgp]], [[8fgq]], [[8fgr]], [[8fgs]], [[8fgt]], [[8fgu]], [[8ufr]], [[8uft]], [[8ufu]], [[9c1z]], [[9cw5]], [[9cw6]], [[9cw7]], [[9cw9]], [[9cwj]], [[9cwk]], [[9mwo]], [[9mws]], [[9mwt]], [[9mwu]], [[9mwv]], [[9mww]], [[9mz1]], [[9mz2]], [[9mz3]], [[9mz4]], [[9q4y]], [[9q51]], [[9q52]], [[9q54]], [[9q55]], [[9q58]] – h-eNOS heme domain + inhibitor<br />
**[[6pou]], [[6pov]], [[6pow]], [[6pox]], [[6poy]], [[6poz]], [[6pp0]], [[6pp1]], [[6pp2]], [[6pp3]], [[6pp4]], [[7m56]], [[7tsg]], [[7tsh]], [[7tsi]], [[7tsk]], [[7tsl]], [[7tsm]], [[7tsn]], [[7tso]], [[7tsp]], [[7uao]], [[8fge]], [[8fgn]], [[8fgo]], [[8fgp]], [[8fgq]], [[8fgr]], [[8fgs]], [[8fgt]], [[8fgu]], [[8ufr]], [[8uft]], [[8ufu]], [[9c1z]], [[9cw5]], [[9cw6]], [[9cw7]], [[9cw9]], [[9cwj]], [[9cwk]], [[9mwo]], [[9mws]], [[9mwt]], [[9mwu]], [[9mwv]], [[9mww]], [[9mz1]], [[9mz2]], [[9mz3]], [[9mz4]], [[9q4y]], [[9q51]], [[9q52]], [[9q54]], [[9q55]], [[9q58]] – h-eNOS heme domain + inhibitor<br />
**[[6ng1]], [[6ng2]], [[6ng4]], [[6ng5]], [[6ng6]], [[6ng7]], [[6ng8]], [[6nga]], [[6ngb]], [[6ngc]], [[6ngd]], [[6nge]], [[6ngf]], [[6ngh]], [[6ngi]] – h-eNOS heme domain (mutant) + inhibitor<br />
**[[6ng1]], [[6ng2]], [[6ng4]], [[6ng5]], [[6ng6]], [[6ng7]], [[6ng8]], [[6nga]], [[6ngb]], [[6ngc]], [[6ngd]], [[6nge]], [[6ngf]], [[6ngh]], [[6ngi]] – h-eNOS heme domain (mutant) + inhibitor<br />
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**[[4kcp]], [[4kcq]], [[4kcr]], [[4kcs]] - r-eNOS OD +thiophene carboximidamide derivative<br />
**[[4kcp]], [[4kcq]], [[4kcr]], [[4kcs]] - r-eNOS OD +thiophene carboximidamide derivative<br />
**[[4uh0]], [[4uh1]], [[4uh2]], [[4uh3]], [[4uh4]], [[4uh7]], [[4uh8]], [[4uh9]], [[4uha]], [[6ngj]], [[6ngk]], [[6ngl]], [[6ngm]], [[6ngn]], [[6ngp]], [[6ngq]], [[6ngr]], [[6ngs]], [[6ngt]], [[6ngu]], [[6ngv]], [[6ngw]], [[6ngx]], [[6ngy]], [[6ngz]], [[6nh0]] – r-eNOS heme domain + inhibitor<br />
**[[4uh0]], [[4uh1]], [[4uh2]], [[4uh3]], [[4uh4]], [[4uh7]], [[4uh8]], [[4uh9]], [[4uha]], [[6ngj]], [[6ngk]], [[6ngl]], [[6ngm]], [[6ngn]], [[6ngp]], [[6ngq]], [[6ngr]], [[6ngs]], [[6ngt]], [[6ngu]], [[6ngv]], [[6ngw]], [[6ngx]], [[6ngy]], [[6ngz]], [[6nh0]] – r-eNOS heme domain + inhibitor<br />
Neuronal NOS;  heme domain 297-718
 
*Neuronal NOS;  heme domain 297-718
 
**[[4uh5]], [[6av3]], [[6av4]], [[6av5]], [[7ts8]], [[7tsf]], [[9cvn]], [[9q4z]] - h-nNOS heme domain +inhibitor<br />
**[[4uh5]], [[6av3]], [[6av4]], [[6av5]], [[7ts8]], [[7tsf]], [[9cvn]], [[9q4z]] - h-nNOS heme domain +inhibitor<br />
**[[4uch]], [[4uh6]], [[5vuv]], [[5vuw]], [[5vux]], [[5vuy]], [[5vuz]], [[5vv1]], [[5vv2]], [[5vv4]], [[6auz]], [[6auy]], [[6av0]], [[6av1]], [[6av2]], [[6cic]], [[6cid]], [[6ng1]], [[6ng2]], [[6ng4]], [[6ng5]], [[6ng6]], [[6ng7]], [[6ng8]], [[6nga]], [[6ngb]], [[6ngc]], [[6ngd]], [[6nge]], [[6ngf]], [[6ngh]], [[6ngi]], [[6nhb]], [[6nhc]], [[6pna]], [[6pnb]], [[6pnc]], [[6pnd]], [[6pne]], [[6pnf]], [[6png]], [[6pnh]], [[6po5]], [[6po7]], [[6po8]], [[6po9]], [[6poa]], [[6pob]], [[6poc]], [[6pot]], [[7ts1]], [[7ts2]], [[7ts3]], [[7ts4]], [[7ts5]], [[7ts6]], [[7ts6]], [[7uam]], [[7us7]], [[7us8]], [[8fgf]], [[8fgg]], [[8fgh]], [[8fgi]], [[8fgk]], [[8fgl]], [[8fgm]], [[9cvo]], [[9cvp]], [[9cvq]], [[9cvs]], [[9cvu]], [[9cvv]], [[9cvx]], [[9cvy]], [[9cvz]], [[9cw0]], [[9cw1]], [[9cw3]], [[9myw]], [[9mwb]], [[9q4i]], [[9q4j]], [[9q4n]], [[9q4o]], [[9q4w]] - h-nNOS heme domain (mutant) +inhibitor<br />
**[[4uch]], [[4uh6]], [[5vuv]], [[5vuw]], [[5vux]], [[5vuy]], [[5vuz]], [[5vv1]], [[5vv2]], [[5vv4]], [[6auz]], [[6auy]], [[6av0]], [[6av1]], [[6av2]], [[6cic]], [[6cid]], [[6ng1]], [[6ng2]], [[6ng4]], [[6ng5]], [[6ng6]], [[6ng7]], [[6ng8]], [[6nga]], [[6ngb]], [[6ngc]], [[6ngd]], [[6nge]], [[6ngf]], [[6ngh]], [[6ngi]], [[6nhb]], [[6nhc]], [[6pna]], [[6pnb]], [[6pnc]], [[6pnd]], [[6pne]], [[6pnf]], [[6png]], [[6pnh]], [[6po5]], [[6po7]], [[6po8]], [[6po9]], [[6poa]], [[6pob]], [[6poc]], [[6pot]], [[7ts1]], [[7ts2]], [[7ts3]], [[7ts4]], [[7ts5]], [[7ts6]], [[7ts6]], [[7uam]], [[7us7]], [[7us8]], [[8fgf]], [[8fgg]], [[8fgh]], [[8fgi]], [[8fgk]], [[8fgl]], [[8fgm]], [[9cvo]], [[9cvp]], [[9cvq]], [[9cvs]], [[9cvu]], [[9cvv]], [[9cvx]], [[9cvy]], [[9cvz]], [[9cw0]], [[9cw1]], [[9cw3]], [[9myw]], [[9mwb]], [[9q4i]], [[9q4j]], [[9q4n]], [[9q4o]], [[9q4w]] - h-nNOS heme domain (mutant) +inhibitor<br />
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**[[6nhd]], [[6nhe]], [[6pmv]], [[6pmw]], [[6pmx]], [[6pmy]], [[6pmz]], [[6pn0]], [[6pn1]], [[6pn2]], [[6pn3]], [[6pn4]], [[6pn5]], [[6pn6]], [[6pn7]], [[6pn8]], [[6pn9]], [[7s3x]], [[7s3y]], [[7s3z]], [[7s40]], [[8fgb]], [[8fgc]] - r-nNOS heme domain +inhibitor<br />
**[[6nhd]], [[6nhe]], [[6pmv]], [[6pmw]], [[6pmx]], [[6pmy]], [[6pmz]], [[6pn0]], [[6pn1]], [[6pn2]], [[6pn3]], [[6pn4]], [[6pn5]], [[6pn6]], [[6pn7]], [[6pn8]], [[6pn9]], [[7s3x]], [[7s3y]], [[7s3z]], [[7s40]], [[8fgb]], [[8fgc]] - r-nNOS heme domain +inhibitor<br />
**[[7ts9]], [[7tsa]], [[7tsb]], [[7tsc]], [[7tsd]], [[7tse]], [[7uan]], [[9cvi]], [[9cvl]], [[9myy]], [[9q4p]], [[9q4r]], [[9q4t]] - r-nNOS heme domain (mutant) + inhibitor<br />
**[[7ts9]], [[7tsa]], [[7tsb]], [[7tsc]], [[7tsd]], [[7tse]], [[7uan]], [[9cvi]], [[9cvl]], [[9myy]], [[9q4p]], [[9q4r]], [[9q4t]] - r-nNOS heme domain (mutant) + inhibitor<br />
Neuronal NOS;  oxygenase domain (OD) 297-718
 
*Neuronal NOS;  oxygenase domain (OD) 297-718
 
**[[2hx2]] – b-nNOS OD+nitroguanidine derivative
**[[2hx2]] – b-nNOS OD+nitroguanidine derivative
**[[3nlv]], [[3nlw]], [[3nlx]], [[3nly]], [[3nlz]], [[3nm0]] - b-nNOS OD + inhibitor
**[[3nlv]], [[3nlw]], [[3nlx]], [[3nly]], [[3nlz]], [[3nm0]] - b-nNOS OD + inhibitor
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**[[1p6h]], [[1p6i]], [[1p6j]], [[1rs6]], [[1rs7]] – r-nNOS OD +dipeptide inhibitor
**[[1p6h]], [[1p6i]], [[1p6j]], [[1rs6]], [[1rs7]] – r-nNOS OD +dipeptide inhibitor
**[[1vag]] – m-nNOS OD+inhibitor – mouse
**[[1vag]] – m-nNOS OD+inhibitor – mouse
*Neuronal NOS;  other domains
*Neuronal NOS;  other domains
**[[8t1j]] - r-nNOS  + Arg – Cryo EM
**[[8t1j]] - r-nNOS  + Arg – Cryo EM
**[[1qau]] - r-nNOS  PDZ domain
**[[1qau]] - r-nNOS  PDZ domain
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**[[1m8d]] – m-iNOS OD+chlorzoxazone
**[[1m8d]] – m-iNOS OD+chlorzoxazone
**[[1m8e]], [[1m8h]], [[1m8i]], [[1m9m]], [[1m9q]] – m-iNOS OD+ indazole derivative
**[[1m8e]], [[1m8h]], [[1m8i]], [[1m9m]], [[1m9q]] – m-iNOS OD+ indazole derivative
**[[3gof]] - c-iNOS OD + calmodulin – chicken<br />
**[[3gof]] - c-iNOS OD + calmodulin – chicken<br />
Prokaryote NOS
 
*Prokaryote NOS
 
**[[2amo]] – BsNOS – ''Bacillus subtilis''
**[[2amo]] – BsNOS – ''Bacillus subtilis''
**[[2an0]], [[2an2]] – BsNOS (mutant)
**[[2an0]], [[2an2]] – BsNOS (mutant)
**[[2fbz]], [[2fc1]], [[2fc2]] – BsNOS+NO
**[[2fbz]], [[2fc1]], [[2fc2]] – BsNOS+NO
**[[1m7v]], [[1m7z]] – BsNOS+THF+ Arg
**[[1m7v]], [[1m7z]] – BsNOS+THF+ Arg
**[[6xcx]], [[6xk3]], [[6xk4]], [[6xk5]], [[6xk6]], [[6xk7]], [6xk8]], [[6xmc]] – BsNOS + inhibitor<br />
**[[6xcx]], [[6xk3]], [[6xk4]], [[6xk5]], [[6xk6]], [[6xk7]], [[6xk8]], [[6xmc]] – BsNOS + inhibitor<br />
**[[4d3v]], [[4d3u]], [[4d3t]], [[4d3o]], [[4d3n]], [[4d3m]], [[4d3k]], [[4d3j]], [[4d3i]], [[4d7h]], [[4d7i]], [[4d7j]], [[4lwa]], [[4lwb]], [[4ug5]], [[4ugy6], [[4ug7]], [[4ug8]], [[4ug9]], [[4uga]], [[4ugb]], [[4ugc]], [[4ugd]], [[4uge]], [[4ugf]], [[4ugg]], [[4ugh]], [[4ugi]], [[4ugj]], [[4ugk]], [[4ugl]], [[4ugm]], [[4ugn]], [[4ugo]], [[4ugp]], [[4ugq]], [[4ugr]], [[4ugs]], [[4ugt]], [[4ugu]], [[4ugv]], [[4ugw]], [[4ugx]], [[4ugy]], [[4uqr]], [[4uqs]], [[5g67]], [[5g6q]], [[5g6p]], [[5g6o]], [[5g6n]], [[5g6m]], [[5g6l]], [[5g6k]], [[5g6j]], [[5g6i]], [[5g6h]], [[5g6g]], [[5g6f]], [[5g6e]], [[5g6d]], [[5g6c]], [[5g6b]], [[5g6a]], [[5g69]], [[5g68]], [[5g66]], [[5g65]] – BsNOS (mutant) + inhibitor<br />
**[[4d3v]], [[4d3u]], [[4d3t]], [[4d3o]], [[4d3n]], [[4d3m]], [[4d3k]], [[4d3j]], [[4d3i]], [[4d7h]], [[4d7i]], [[4d7j]], [[4lwa]], [[4lwb]], [[4ug5]], [[4ug6]], [[4ug7]], [[4ug8]], [[4ug9]], [[4uga]], [[4ugb]], [[4ugc]], [[4ugd]], [[4uge]], [[4ugf]], [[4ugg]], [[4ugh]], [[4ugi]], [[4ugj]], [[4ugk]], [[4ugl]], [[4ugm]], [[4ugn]], [[4ugo]], [[4ugp]], [[4ugq]], [[4ugr]], [[4ugs]], [[4ugt]], [[4ugu]], [[4ugv]], [[4ugw]], [[4ugx]], [[4ugy]], [[4uqr]], [[4uqs]], [[5g67]], [[5g6q]], [[5g6p]], [[5g6o]], [[5g6n]], [[5g6m]], [[5g6l]], [[5g6k]], [[5g6j]], [[5g6i]], [[5g6h]], [[5g6g]], [[5g6f]], [[5g6e]], [[5g6d]], [[5g6c]], [[5g6b]], [[5g6a]], [[5g69]], [[5g68]], [[5g66]], [[5g65]] – BsNOS (mutant) + inhibitor<br />
**[[2flq]] – NOS+ Arg – ''Geobacillus stearothermophilus''
**[[2flq]] – NOS+ Arg – ''Geobacillus stearothermophilus''
**[[9q0x]] – NOS – ''Synechococcus'' – Cryo EM
**[[9q0x]] – NOS – ''Synechococcus'' – Cryo EM
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