Nucleoprotein 3D structures: Difference between revisions

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Line 101: Line 101:
**[[9umz]] - NP + RNA – SFTS virus - Cryo EM<br />
**[[9umz]] - NP + RNA – SFTS virus - Cryo EM<br />
**[[9jzl]] – BdvNP + RNA – Cryo EM<br/`>
**[[9jzl]] – BdvNP + RNA – Cryo EM<br/`>


*Nucleoprotein complex with antibody
*Nucleoprotein complex with antibody
Line 107: Line 106:
**[[5uk4]] - VvNP + nanobody + RNA<br />
**[[5uk4]] - VvNP + nanobody + RNA<br />
**[[5tjw]] - IvNP + nanobody <br />
**[[5tjw]] - IvNP + nanobody <br />
**[[6app]], [[4w2q]], [[4w2o]] - LvmvNP C-terminal + nanobody <br />
**[[4w2q]], [[4w2o]], [[6app]] - LvmvNP C-terminal + nanobody <br />
**[[5w2b]] - NP + antibody – Reston Ebolavirus<br />
**[[5w2b]] - NP + antibody – Reston Ebolavirus<br />
**[[5vkd]] - NP C-terminal + antibody – Bundibugyo Ebolavirus<br />
**[[5vkd]] - NP C-terminal + antibody – Bundibugyo Ebolavirus<br />
**[[6u55]], [[6u54]], [[6u52]], [[6u51]] - NP C-terminal + antibody – Sudan Ebolavirus<br />
**[[6u51]], [[6u52]], [[6u54]], [[6u55]] - NP C-terminal + antibody – Sudan Ebolavirus<br />
**[[5uk4]] - VvNP + nanobody + RNA<br />
**[[5uk4]] - VvNP + nanobody + RNA<br />


Line 120: Line 119:
**[[2wyy]] – VvNP + poly U – Cryo EM<br />
**[[2wyy]] – VvNP + poly U – Cryo EM<br />
**[[3hhw]], [[3pmk]] – VvNP + phosphoprotein<br />r />
**[[3hhw]], [[3pmk]] – VvNP + phosphoprotein<br />r />
**[[4co6]] - NvNP + phosphoprotein – Nipah virus<br />
**[[4co6]] - NvNP + phosphoprotein <br />
**[[8b8v]] - RvNP + phosphoprotein <br />
**[[8b8v]] - RvNP + phosphoprotein <br />
**[[8fwl]] – LvaNP/phosphoprotein <br />
**[[8u0a]], [[8u0b]] - NP + phosphoprotein – Lyssavirus rabies<br />
**[[7ev8]] - NP + phosphoprotein – Human respirovirus<br />
**[[7ev8]] - NP + phosphoprotein – Human respirovirus<br />
**[[4ucc]] – RsvNP N terminal + inhibitor<br />
**[[4ucc]] – RsvNP N terminal + inhibitor<br />
**[[4ucb]], [[4uca]] – RsvNP N terminal + phosphoprotein<br />
**[[4uca]], [[4ucb]] – RsvNP N terminal + phosphoprotein<br />
**[[4uc9]], [[4uc8]] – RsvNP N terminal + phosphoprotein peptide<br />
**[[4uc8]], [[4uc9]] – RsvNP N terminal + phosphoprotein peptidebr />
**[[3ro5]], [[4dya]], [[4dyb]], [[4dyn]], [[4dyp]], [[3tg6]], [[6j1u]] – IvNP + ligand<br />
**[[3ro5]], [[3tg6]], [[4dya]], [[4dyb]], [[4dyn]], [[4dyp]], [[6j1u]] – IvNP + ligand
**[[9oug]] – IvNP + inhibitor <br/ >
**[[6h9g]] - IvNP + peptide – Cryo EM<br />
**[[6h9g]] - IvNP + peptide – Cryo EM<br />
**[[4ypi]] - EvNP + peptide – Cryo EM<br />
**[[4ypi]] - EvNP + peptide – Cryo EM<br />
**[[6ehm]] - EvNP + VP24 – Cryo EM<br />
**[[6ehm]] - EvNP + VP24 – Cryo EM<br />
**[[8usn]], [[8ust]], [[8y9j]] - EvNP + VP24 + RNA – Cryo EM<br />
**[[5vao]], [[5vap]] - EvNP VP30 C-terminal 139-267 + NP peptide <br />
**[[5vao]], [[5vap]] - EvNP VP30 C-terminal 139-267 + NP peptide <br />
**[[6e5x]] - EvNP VP30 C-terminal + RBBP6 peptide <br />
**[[6e5x]] - EvNP VP30 C-terminal + RBBP6 peptide <br />
Line 135: Line 138:
**[[5ip3]] - TsvNP + DNA <br />
**[[5ip3]] - TsvNP + DNA <br />
**[[5fvd]] - HmpvNP + phosphoprotein<br />
**[[5fvd]] - HmpvNP + phosphoprotein<br />
**[[8pdp]] - HmpvNP + phosphoprotein + RNA – Cryo EM<br />
**[[5wkn]] - PivNP + phosphoprotein<br />
**[[5wkn]] - PivNP + phosphoprotein<br />
**[[6kl5]], [[6kl6]], [[6lnn]], [[6lz6]], [[6lz8]], [[7dyd]] – McvNP N terminal + inhibitor<br />
**[[6kl5]], [[6kl6]], [[6lnn]], [[6lz6]], [[6lz8]], [[7dyd]] – McvNP N terminal + inhibitor<br />


*Nucleoprotein from SARS-Covid 2
*Nucleoprotein from SARS-Covid 2; Domains – N terminal or RNA-binding 45-181; C terminal dimerization 257-364; C terminal 244-419


**[[6vyo]], [[6wkp]], [[6yi3]], [[7cdz]], [[4j3k]], [[5n4k]], [[2ofz]], [[2og3]], [[6m3m]], [[7cdz]], [[7uw3]], [[7vbd]], [[7vbf]], [[7vnu]], [[7xx1]] - ScvNP N terminal 45-181 <br />
**[[9otw]], [[9ouc]] - ScvNP 8-498 + inhibitor<br />
**[[1ssk]], [[7sd4]] - ScvNP N terminal – NMR<br />
**[[2ofz]], [[2og3]], [[4j3k]], [[5n4k]], [[6m3m]], [[6vyo]], [[6wkp]], [[6yi3]], [[7cdz]], [[7uw3]], [[7vbd]], [[7vbf]], [[7vnu]], [[7xx1]], [[8iqj]], [[8x1h]], [[9exb]] - ScvNP N terminal <br />
**[[9evy]], [[9ewh]], [[9ezb]], [[9f5j]], [[9f5l]], [[9f7a]], [[9f7c]], [[9f83]], [[9fbg]] - ScvNP N terminal (mutant)<br />
**[[1ssk]], [[7sd4]], [[9qwi]] - ScvNP N terminal – NMR<br />
**[[7acs]], [[7act]] - ScvNP N terminal + RNA - NMR<br />
**[[7acs]], [[7act]] - ScvNP N terminal + RNA - NMR<br />
**[[8tfd]], [[8zbf]], [[9cj6]] - ScvNP N terminal + DNA <br />
**[[8iv3]], [[8j6x]] - ScvNP N terminal + inhibitor <br />
**[[7cr5]], [[7n3c]], [[7n3d]], [[7str]], [[7sts]], [[7sue]] - ScvNP N-terminal + antibody <br />
**[[7cr5]], [[7n3c]], [[7n3d]], [[7str]], [[7sts]], [[7sue]] - ScvNP N-terminal + antibody <br />
**[[7n0r]], [[7r98]] – ScvNP N-terminal + nanobody <br />
**[[7n0r]], [[7r98]] – ScvNP N-terminal + nanobody <br />
**[[4kxj]] – ScvNP N terminal + PJ34 <br />
**[[4kxj]] – ScvNP N terminal + PJ34 <br />
**[[4li4]], [[4lm7]], [[4lm9]], [[4lmc]], [[7o35]], [[7o36]], [[7xxk]] – ScvNP N terminal + nucleotide <br />
**[[4li4]], [[4lm7]], [[4lm9]], [[4lmc]], [[7o35]], [[7o36]], [[7xxk]], [[9kn1]] – ScvNP N terminal + nucleotide <br />
**[[9s3n]] – ScvNP N terminal + peptide <br />
**[[4lmt]] – ScvNP N terminal + quinoline derivative <br />
**[[4lmt]] – ScvNP N terminal + quinoline derivative <br />
**[[6wji]], [[6wzo]], [[6wzq]], [[6yun]], [[6zco]], [[7c22]], [[7ce0]], [[5epw]], [[2gib]], [[7c22]], [[7de1]], [[7f2b]], [[7f2e]], [[7o05]], [[7uxx]], [[7vbe]], [[7xwx]] - ScvNP C terminal dimerization domain 257-364 <br />
**[[2gib]], [[5epw]], [[6wji]], [[6wzo]], [[6wzq]], [[6yun]], [[6zco]], [[7c22]], [[7ce0]], [[7de1]], [[7f2b]], [[7f2e]], [[7o05]], [[7uxx]], [[7vbe]], [[7xwx]], [[8r6e]], [[9f2g]], [[9in1]] - ScvNP C terminal dimerization domain <br />
**[[2jw8]] - ScvNP C terminal dimerization domain - NMR <br />
**[[2jw8]] - ScvNP C terminal dimerization domain - NMR <br />
**[[7n0i]] – ScvNP C-terminal + nanobody <br />
**[[7n0i]] – ScvNP C-terminal + nanobody <br />
**[[9c2h]], [[9kur]] – ScvNP C-terminal dimerization domain + antibody – Cryo EM<br />
**[[9rxl]] – ScvNP C-terminal dimerization domain + peptide <br />
**[[7uxz]] – ScvNP C-terminal + chicoric acid <br />
**[[7uxz]] – ScvNP C-terminal + chicoric acid <br />
**[[9f2i]] – ScvNP C-terminal + inhibitor<br />
**[[8w6w]], [[8zfv]], [[9f2h]] – ScvNP C-terminal + drug<br />
**[[7pku]] – ScvNP 191-263 + 3C-like proteinase <br />


*'''Ribonucleoprotein'''
*'''Ribonucleoprotein'''
Line 157: Line 171:
**[[2lbw]] – yRNP subunit 2 residues 36-156 (mutant) – yeast – NMR<br />
**[[2lbw]] – yRNP subunit 2 residues 36-156 (mutant) – yeast – NMR<br />
**[[2lbx]] - yRNP subunit 2 residues 36-156 – NMR<br />
**[[2lbx]] - yRNP subunit 2 residues 36-156 – NMR<br />
**[[4h5l]], [[4csg]], [[5fva]] – TvRNP – Toscana virus<br />
**[[4csg]], [[4h5l]], [[5fva]] – TvRNP – Toscana virus
**[[4csf]] – TvRNP + RNA<br />
**[[4csf]] – TvRNP + RNA<br />
**[[8rcq]] – TvRNP + nanobody<br />
**[[8rcq]] – TvRNP + nanobody<br />
Line 164: Line 178:
*'''Small nuclear ribonucleoprotein'''
*'''Small nuclear ribonucleoprotein'''


**[[2a3j]], [[1fht]] - h-snRNP U1 A RRM – human - NMR<br />
**[[1fht]], [[2a3j]] - h-snRNP U1 A RRM - NMR<br />
**[[7lhx]] - h-snRNP U1 A  (mutant) <br />
**[[7lhx]] - h-snRNP U1 A  (mutant) <br />
**[[2u1a]] - h-snRNP U1 A RRM (mutant) – NMR<br />
**[[2u1a]] - h-snRNP U1 A RRM (mutant) – NMR<br />
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**[[3p49]] - h-snRNP A RRM + glycine riboswitch RNA<br />
**[[3p49]] - h-snRNP A RRM + glycine riboswitch RNA<br />
**[[3iwn]], [[7d7v]] - h-snRNP U1 A RRM (mutant) + riboswitch RNA<br />
**[[3iwn]], [[7d7v]] - h-snRNP U1 A RRM (mutant) + riboswitch RNA<br />
**[[3pgw]], [[3mum]], [[3mur]], [[3mut]], [[3muv]], [[3egz]] - h-snRNP U1 A + DNA riboswitch<br />
**[[3egz]], [[3mum]], [[3mur]], [[3mut]], [[3muv]], [[3pgw]] - h-snRNP U1 A + DNA riboswitch<br />
**[[3mxh]], [[3irw]] - h-snRNP U1 A (mutant) + DNA riboswitch<br />
**[[3irw]], [[3mxh]] - h-snRNP U1 A (mutant) + DNA riboswitch<br />
**[[3bo2]], [[3bo3]], [[3bo4]], [[6sqn]] - h-snRNP U1 A RRM + RNA<br />
**[[3bo2]], [[3bo3]], [[3bo4]], [[6sqn]] - h-snRNP U1 A RRM + RNA<br />
**[[3k0j]], [[1drz]], [[1m5k]], [[1m5o]], [[1m5p]], [[1m5v]], [[1u6b]], [[3ucu]], [[3ucz]], [[3ud3]], [[3ud4]] - h-snRNP U1 A (mutant) + RNA<br />
**[[1drz]], [[1m5k]], [[1m5o]], [[1m5p]], [[1m5v]], [[1u6b]], [[3k0j]], [[3ucu]], [[3ucz]], [[3ud3]], [[3ud4]] - h-snRNP U1 A (mutant) + RNA<br />
**[[1aud]] - h-snRNP U1 A (mutant) + RNA - NMR<br />
**[[1aud]] - h-snRNP U1 A (mutant) + RNA - NMR<br />
**[[6lau]] - h-snRNP U1 A (mutant) + RNA + SAH<br />
**[[6lau]] - h-snRNP U1 A (mutant) + RNA + SAH<br />
**[[6lax]], [[6las]], [[6laz]] - h-snRNP U1 A (mutant) + RNA + SAM<br />
**[[6las]], [[6lax]], [[6laz]] - h-snRNP U1 A (mutant) + RNA + SAM<br />
**[[1sj3]], [[1sj4]], [[1sjf]], [[1vbx]], [[1vby]], [[1vbz]], [[1vc0]], [[1vc5]], [[1vc6]], [[4prf]] - h-snRNP U1 A (mutant) + Hepatitis ribozyme<br />
**[[1sj3]], [[1sj4]], [[1sjf]], [[1vbx]], [[1vby]], [[1vbz]], [[1vc0]], [[1vc5]], [[1vc6]], [[4prf]] - h-snRNP U1 A (mutant) + Hepatitis ribozyme<br />
**[[3r1h]], [[3r1l]] - h-snRNP U1 A (mutant) + ribozyme<br />
**[[3r1h]], [[3r1l]] - h-snRNP U1 A (mutant) + ribozyme<br />
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**[[3b02]], [[3b03]], [[3b04]] - h-snRNP U1 A RRM1 + group I intron + RNA<br />
**[[3b02]], [[3b03]], [[3b04]] - h-snRNP U1 A RRM1 + group I intron + RNA<br />
**[[1zzn]] - h-snRNP U1 A RRM1 (mutant) + group I intron + RNA<br />
**[[1zzn]] - h-snRNP U1 A RRM1 (mutant) + group I intron + RNA<br />
**[[3l3c]], [[3g8s]], [[3g8t]], [[3g96]], [[3g9c]], [[2nz4]] - h-snRNP U1 A (mutant) + GLMS ribozyme + RNA<br />
**[[2nz4]], [[3g8s]], [[3g8t]], [[3g96]], [[3g9c]], [[3l3c]] - h-snRNP U1 A (mutant) + GLMS ribozyme + RNA
**[[3hhn]] - h-snRNP U1 A (mutant) + class I ligase ribozyme<br />
**[[3hhn]] - h-snRNP U1 A (mutant) + class I ligase ribozyme<br />
**[[2oih]], [[2oj3]] - h-snRNP U1 A + HDV ribozyme<br />
**[[2oih]], [[2oj3]] - h-snRNP U1 A + HDV ribozyme<br />
Line 241: Line 255:
**[[7zir]] - h-hnRNP DL – Cryo EM<br />
**[[7zir]] - h-hnRNP DL – Cryo EM<br />
**[[2hgl]], [[2hgm]], [[2hgn]] - h-hnRNP F QRRM1 – NMR<br />
**[[2hgl]], [[2hgm]], [[2hgn]] - h-hnRNP F QRRM1 – NMR<br />
**[[1wg5]], [[1wez]], [[2lxu]] - h-hnRNP H RRM1 – NMR<br />
**[[1wez]], [[1wg5]], [[2lxu]] - h-hnRNP H RRM1 – NMR<br />
**[[7zug]] - h-hnRNP H1 RRM2 <br />
**[[7zug]] - h-hnRNP H1 RRM2 <br />
**[[6dg1]] - h-hnRNP H2 RRM2 – NMR<br />
**[[6dg1]] - h-hnRNP H2 RRM2 – NMR<br />
Line 249: Line 263:
**[[6kor]] - h-hnRNP Q RRM 242-428<br />
**[[6kor]] - h-hnRNP Q RRM 242-428<br />
**[[3r27]], [[3t08]] - h-hnRNP L RRM<br />
**[[3r27]], [[3t08]] - h-hnRNP L RRM<br />
**[[2do0]], [[2dh9]], [[2dgv]] - h-hnRNP M RRM3 – NMR<br />
**[[2dgv]], [[2dh9]], [[2do0]] - h-hnRNP M RRM3 – NMR
**[[2dgu]] - h-hnRNP Q RRM3 – NMR<br />
**[[2dgu]] - h-hnRNP Q RRM3 – NMR<br />
**[[2dk2]] - h-hnRNP R RRM3 – NMR<br />
**[[2dk2]] - h-hnRNP R RRM3 – NMR<br />
Line 260: Line 274:


**[[2kfy]], [[2kg0]], [[2kg1]] - h-hnRNP F QRRM2 + DNA – NMR<br />
**[[2kfy]], [[2kg0]], [[2kg1]] - h-hnRNP F QRRM2 + DNA – NMR<br />
**[[2z5n]], [[2z5o]], [[2ot8]] - h-hnRNP D0 CTD 332-355 + transportin-1<br />
**[[2ot8]], [[2z5n]], [[2z5o]] - h-hnRNP D0 CTD 332-355 + transportin-1<br />
**[[1u1k]], [[1u1l]], [[1u1m]], [[1u1n]], [[1u1o]], [[1u1p]], [[1u1q]], [[1u1r]], [[1up1]] - h-hnRNP A1 RRM1-2 + DNA<br />
**[[1u1k]], [[1u1l]], [[1u1m]], [[1u1n]], [[1u1o]], [[1u1p]], [[1u1q]], [[1u1r]], [[1up1]] - h-hnRNP A1 RRM1-2 + DNA<br />
**[[6dcl]] - h-hnRNP A1 RRM1-2+ RNA<br />
**[[6dcl]] - h-hnRNP A1 RRM1-2+ RNA<br />
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