25rg: Difference between revisions
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Created page with "'''Unreleased structure''' The entry 25rg is ON HOLD Authors: Chen, S.D., Li, X. Description: CyroEM structure of the complex between Shiga toxin Stx1a B subunit and neutralising Fab fragment of RDS045 Category: Unreleased Structures Category: Li, X Category: Chen, S.D" |
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==CyroEM structure of the complex between Shiga toxin Stx1a B subunit and neutralising Fab fragment of RDS045== | |||
<StructureSection load='25rg' size='340' side='right'caption='[[25rg]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[25rg]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Shigella_dysenteriae Shigella dysenteriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=25RG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=25RG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=25rg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=25rg OCA], [https://pdbe.org/25rg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=25rg RCSB], [https://www.ebi.ac.uk/pdbsum/25rg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=25rg ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Chen | == Function == | ||
[https://www.uniprot.org/uniprot/STXB_SHIDS STXB_SHIDS] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Shigella dysenteriae]] | |||
[[Category: Chen SD]] | |||
[[Category: Li X]] | |||