9tiv: Difference between revisions
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==cryo-EM structure of MscL G22S mutant from Escherichia coli in MSP nanodisc== | |||
<StructureSection load='9tiv' size='340' side='right'caption='[[9tiv]], [[Resolution|resolution]] 3.46Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9tiv]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9TIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9TIV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.46Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9tiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9tiv OCA], [https://pdbe.org/9tiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9tiv RCSB], [https://www.ebi.ac.uk/pdbsum/9tiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9tiv ProSAT]</span></td></tr> | ||
[[Category: Lange | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/MSCL_ECOLI MSCL_ECOLI] Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition.<ref>PMID:10202137</ref> <ref>PMID:23416054</ref> <ref>PMID:23875651</ref> <ref>PMID:7511799</ref> <ref>PMID:9632260</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Lange A]] | |||
[[Category: Sprink T]] | |||
[[Category: Xiao T]] | |||
Latest revision as of 08:06, 9 September 2026
cryo-EM structure of MscL G22S mutant from Escherichia coli in MSP nanodisc
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