13dt: Difference between revisions

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Created page with "'''Unreleased structure''' The entry 13dt is ON HOLD Authors: Mallette, E., Singer, A.U., Blazer, L.L., Adams, J.J., Suits, M.D.L., Sidhu, S.S. Description: Structure of FabS1CE2_P4a in complex with the N-terminal domain of PD-L1 Category: Unreleased Structures Category: Mallette, E Category: Sidhu, S.S Category: Blazer, L.L Category: Suits, M.D.L Category: Adams, J.J Category: Singer, A.U"
 
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'''Unreleased structure'''


The entry 13dt is ON HOLD
==Structure of FabS1CE2_P4a in complex with the N-terminal domain of PD-L1==
 
<StructureSection load='13dt' size='340' side='right'caption='[[13dt]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
Authors: Mallette, E., Singer, A.U., Blazer, L.L., Adams, J.J., Suits, M.D.L., Sidhu, S.S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[13dt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=13DT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=13DT FirstGlance]. <br>
Description: Structure of FabS1CE2_P4a in complex with the N-terminal domain of PD-L1
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
[[Category: Mallette, E]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=13dt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=13dt OCA], [https://pdbe.org/13dt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=13dt RCSB], [https://www.ebi.ac.uk/pdbsum/13dt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=13dt ProSAT]</span></td></tr>
[[Category: Sidhu, S.S]]
</table>
[[Category: Blazer, L.L]]
== Function ==
[[Category: Suits, M.D.L]]
[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>
[[Category: Adams, J.J]]
== References ==
[[Category: Singer, A.U]]
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Adams JJ]]
[[Category: Blazer LL]]
[[Category: Mallette E]]
[[Category: Sidhu SS]]
[[Category: Singer AU]]
[[Category: Suits MDL]]
Retrieved from "https://proteopedia.org/13dt"