26jz: Difference between revisions

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'''Unreleased structure'''


The entry 26jz is ON HOLD  until Paper Publication
==Cryo-EM structure of Crimean-Congo hemorrhagic fever virus RNA polymerase in complex with 5'/3' vRNA dual-promotor==
 
<StructureSection load='26jz' size='340' side='right'caption='[[26jz]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
Authors: Ma, J., Yang, K., Wu, H., Liu, X., LIang, Z.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[26jz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Orthonairovirus_haemorrhagiae Orthonairovirus haemorrhagiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=26JZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=26JZ FirstGlance]. <br>
Description: Cryo-EM structure of Crimean-Congo hemorrhagic fever virus RNA polymerase in complex with 5''/3'' vRNA dual-promotor
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Ma, J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=26jz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=26jz OCA], [https://pdbe.org/26jz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=26jz RCSB], [https://www.ebi.ac.uk/pdbsum/26jz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=26jz ProSAT]</span></td></tr>
[[Category: Liu, X]]
</table>
[[Category: Yang, K]]
== Function ==
[[Category: Wu, H]]
[https://www.uniprot.org/uniprot/L_CCHFI L_CCHFI] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity.
[[Category: Liang, Z]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Orthonairovirus haemorrhagiae]]
[[Category: Liang Z]]
[[Category: Liu X]]
[[Category: Ma J]]
[[Category: Wu H]]
[[Category: Yang K]]
Retrieved from "https://proteopedia.org/26jz"