2bbw: Difference between revisions

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New page: left|200px<br /> <applet load="2bbw" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bbw, resolution 2.05Å" /> '''Crystal structure o...
 
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[[Image:2bbw.gif|left|200px]]<br />
<applet load="2bbw" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2bbw, resolution 2.05&Aring;" />
'''Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate'''<br />


==About this Structure==
==Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate==
2BBW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with GP5 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Adenylate_kinase Adenylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BBW OCA].  
<StructureSection load='2bbw' size='340' side='right'caption='[[2bbw]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
[[Category: Adenylate kinase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2bbw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GP5:DIGUANOSINE-PENTAPHOSPHATE'>GP5</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbw OCA], [https://pdbe.org/2bbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbw RCSB], [https://www.ebi.ac.uk/pdbsum/2bbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KAD4_HUMAN KAD4_HUMAN] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/2bbw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bbw ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith C]]
[[Category: Bunkoczi, G.]]
[[Category: Bunkoczi G]]
[[Category: Debreczeni, J.]]
[[Category: Debreczeni J]]
[[Category: Delft, F.von.]]
[[Category: Edwards A]]
[[Category: Edwards, A.]]
[[Category: Fedorov O]]
[[Category: Fedorov, O.]]
[[Category: Filippakopoulos P]]
[[Category: Filippakopoulos, P.]]
[[Category: Knapp S]]
[[Category: Knapp, S.]]
[[Category: Niesen F]]
[[Category: Niesen, F.]]
[[Category: Sundstrom M]]
[[Category: SGC, Structural.Genomics.Consortium.]]
[[Category: Turnbull AP]]
[[Category: Sundstrom, M.]]
[[Category: Ugochukwu E]]
[[Category: Turnbull, A.P.]]
[[Category: Weigelt J]]
[[Category: Ugochukwu, E.]]
[[Category: Von Delft F]]
[[Category: Weigel, J.]]
[[Category: GP5]]
[[Category: ak4]]
[[Category: human]]
[[Category: nucleotide binding]]
[[Category: nucleotide kinase]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 21:00:46 2007''
Retrieved from "https://proteopedia.org/2bbw"