Pyruvate kinase 3D structures: Difference between revisions

 

**[[1t5a]], [[1zjh]], [[3bjf]], [[3bjt]], [[9hib]] - hPyK M2 muscle - human

**[[3g2g]], [[4qg6]], [[4qg8]], [[4qg9]], [[4qgc]], [[4wj8]], [[4yj5]], [[6b6u]], [[8hgf]] - hPyK M2 muscle (mutant)

**[[3srf]], [[3srh]] – hPyK M1 muscle

**[[6wp3]], [[6wp4]], [[6wp5]], [[6wp6]] – hPyK M2 muscle (mutant)

**[[1pkm]], [[1pyk]] – PyK muscle – cat

**[[1f3w]], [[8f5t]] – rPyK muscle – rabbit

**[[1f3x]], [[7r6y]] - rPyK muscle (mutant)

**[[4b2d]], [[9hic]] - hPyK M2 muscle + fructose bisphosphate

**[[4rpp]] - hPyK M2 muscle (mutant) + fructose bisphosphate

**[[4fxj]] - hPyK M2 muscle + phenylalanine

**[[6gg3]] - hPyK M2 muscle + alanine

**[[6gg4]] - hPyK M2 muscle + phenylalanine

**[[6gg5]] - hPyK M2 muscle + tryptophan

**[[6gg6]] - hPyK M2 muscle + serine

**[[6nub]] - hPyK M2 muscle (mutant) + serine

**[[6nu1]] - hPyK M2 muscle + cysteine

**[[6nu5]] - hPyK M2 muscle (mutant) + cysteine

**[[6ttf]], [[6tti]], [[6ttq]] - hPyK M2 muscle + inhibitor – Cryo EM

**[[6tth]] - hPyK M2 muscle + threonine – Cryo EM

**[[6v74]], [[6v75]] - hPyK M2 muscle + asparagine

**[[6v76]] - hPyK M2 muscle + valine

**[[8g2e]], [[9iqq]], [[9o3b]] - hPyK M2 muscle + activator

**[[8f5u]] - rPyK muscle + pyruvate

**[[3me3]] – hPyK M1/M2 muscle + aniline derivative + fructose bisphosphate

**[[4g1n]] - hPyK M1/M2 muscle + pyridazine derivative + oxalate

**[[3h6o]] - hPyK M1/M2 muscle + pyridazine derivative + fructose bisphosphate

**[[3gqy]], [[3gr4]], [[3u2z]] - hPyK M1/M2 muscle + piperazine derivative + fructose bisphosphate

**[[8hmq]], [[8hmr]], [[8hms]], [[8hmu]] - hPyK muscle (mutant) + Pi + fructose bisphosphate

**[[5x0i]] - hPyK M2 muscle (mutant) + serine + fructose bisphosphate

**[[7l21]] - hPyK M2 muscle (mutant) + oxalate + fructose bisphosphate

**[[6jfb]] - hPyK M2 muscle + serine + phosphate

**[[5x1v]], [[5x1w]] - hPyK M2 muscle + activator + fructose bisphosphate

**[[4jpg]] - hPyK M1/M2 muscle + pyrimidine derivative +fructosebisphosphate

**[[3srd]] - hPyK M1/M2 muscle + oxalate + fructose bisphosphate

**[[4fxf]] - hPyK M1/M2 muscle + oxalate + ATP + fructose bisphosphate

**[[3n25]] – rPyK M1/M2 muscle + proline + Mn + pyruvate

**[[2g50]] - rPyK M1/M2 muscle + alanine + Mn + pyruvate

**[[8f6m]] - rPyK muscle + Ala + Mn + ADP

**[[1pkn]] - rPyK muscle + Mn + pyruvate

**[[1aqf]] – rPyK muscle + Mg + phospholactate

**[[1a49]], [[1a5u]] - rPyK muscle + ATP + oxalate

 

**[[9vxp]] - hPyK liver – Cryo EM

**[[2vgb]] – hPyK liver  

**[[2vgf]], [[2vgg]], [[2vgi]] [[6nn5]], [[6nn7]], [[6nn8]], [[7qdn]] – hPyK liver (mutant)

**[[9w4q]], [[9w7y]], [[9w81]] - hPyK liver + activator – Cryo EM

**[[8tbs]], [[8tbt]], [[8tbu]] - hPyK liver + activator

**[[7fs7]] - hPyK liver + modulator

**[[9wdo]], [[9wdq]], [[9wdr]], [[9edt]] - hPyK liver + drug – Cryo EM

**[[8xfd]] - hPyK liver + activator

**[[9r3h]], [[9r3i]], [[9r3l]], [[9r3m]], [[9r3o]], [[9rdf]], [[9rfq]], [[9rft]] - hPyK liver + fluorescent probe

**[[9wez]] - hPyK liver + fructose bisphosphate – Cryo EM

**[[6nn4]] - hPyK M2 liver (mutant) + fructose bisphosphate

**[[6ech]], [[6eck]] - PyK liver + fructose bisphosphate - rat

**[[5sc8]], [[5sc9]], [[5sca]], [[5scb]], [[5scc]], [[5scd]], [[5sce]], [[5scf]], [[5scg]], [[5sch]], [[5sci]], [[5scj]], [[5sck]], [[5scl]], [[5sdt]], [[7qzu]] - hPyK liver + anthracene derivative + fructose bisphosphate

**[[7frv]], [[7frw]], [[7frx]], [[7fry]], [[7frz]], [[7fs0]], [[7fs1]], [[7fs2]], [[7fs3]], [[7fs4]], [[7fs5]], [[7fs6]], [[7fs8]], [[7fs9]], [[7fsa]], [[7fsb]], [[7fsc]], [[7fsd]] - hPyK liver + modulator + fructose bisphosphate

**[[4ima]], [[4ip7]] - hPyK liver (mutant) + citrate + adenosine + fructose bisphosphate

**[[6du6]] – PyK - mosquito

**[[1pky]], [[4yng]], [[6k0k]] – EcPyK - Eschericia coli

**[[1e0t]], [[1e0u]], [[8edq]], [[8edr]], [[8eds]], [[8edt]], [[8eq0]], [[8eq1]], [[8eq3]], [[8eu4]] - EcPyK (mutant)

**[[3t05]], [[3t0t]] – SaPyK – Staphylococcus aureus

**[[3qtg]] – PyK – Pyrobaculum aerophilum

**[[4krz]] – TcPyK – Trypanosoma cruzei

**[[5wrp]] - MtPyK – Mycobacterium tuberculosis

**[[1pkl]], [[3e0w]], [[3hqn]] – LmPyK – Leishmania mexicana

**[[3khd]], [[7z4m]] – PfPyK – Plasmodium falciparum

**[[7z4q]], [[7z4r]] - PfPyK (mutant)

**[[3eoe]], [[3gg8]] – PyK – Toxoplasma gondii

**[[3ma8]], [[4drs]] – CpPyK – Cryptosporidium parvum

**[[2e28]] - PyK (mutant) – Geobacillus stearothermophilus

**[[7oo1]] – PaPyK – Pseudomonas aeruginosa

**[[7ueh]] – PyK – Zymomonas mobilis

**[[8ias]] - SpPyK – Streptococcus pneumoniae

**[[8x4r]] – hPyK + Phe

**[[3qv9]] – TcPyK + Ponceau S

**[[3qv6]] – LmPyK + acid blue 80

**[[3e0v]] – LmPyK + sulfate

**[[3hqq]] - LmPyK + fructose bisphosphate

**[[3qv8]] – LmPyK + benzothiazole

**[[3pp7]] – LmPyK + suramin

**[[3is4]], [[3ktx]] – LmPyK + pyrenetetrasulfonic acid

**[[3t07]] – SaPyK + bis-indole alkaloid

**[[4hyw]] – TbPyK + fructose bisphosphate – Trypanosoma brucei

**[[6su1]], [[6su2]] – PyK + citrate – Trypanosoma congolense

**[[5ws8]] - MtPyK + oxalate

**[[6p0y]] - CpPyK + ADP

**[[8iav]] - SpPyK + fructose bisphosphate

**[[8iat]] - SpPyK + oxalate

**[[8iaw]] - SpPyK + phosphoenolpyruvate

**[[7z4n]] -PfPyK + pyruvate

**[[8rtf]], [[8rvr]] -PyK + antibody – Trypanosoma congolense

**[[8xfd]] – hPyK + activator + fructose bisphosphate

**[[1a3w]] – yPyK + Mn + phosphoglycolic acid + fructose bisphosphate – yeast

**[[1a3x]] - yPyK + Mn + phosphoglycolic acid

**[[4hyv]] – TbPyK + phosphoenolpyruvate + fructose bisphosphate

**[[4kct]] – TbPyK + pyruvate + fructose bisphosphate

**[[4kcu]] – TbPyK + malate + fructose bisphosphate

**[[4kcv]] – TbPyK + oxoglutarate + fructose bisphosphate

**[[4kcw]] – TbPyK + oxalate + fructose bisphosphate

**[[4ks0]] – TcPyK + oxalate + fructose bisphosphate

**[[5ws9]] – MtPyK + oxalate + AMP + ATP

**[[5wsa]] – MtPyK + oxalate + glucose-6-phosphate

**[[5wsb]], [[5wsc]] – MtPyK + oxalate + glucose-6-phosphate + AMP

**[[6ito]] – MtPyK + oxalate + ribose-5-phosphate + AMP

**[[3hqo]] – LmPyK + ATP + oxalate

**[[3hqp]] - LmPyK + ATP + oxalate + fructose bisphosphate

**[[3qv7]] – LmPyK + acid blue 25 + Ponceau S

**[[3srk]] – LmPyK + saccharine + inhibitor

**[[6qxl]] – PaPyK + malonate + glucose-6-phosphate + Mg

**[[6ksh]] – PfPyK + oxalate + ATP

**[[8iax]] - SpPyK + fructose bisphosphate + phosphoenolpyruvate

**[[8iau]] - SpPyK + fructose bisphosphate + oxalate

**[[8xw6]], [[8xw7]], [[8xw8]], [[8xw9]], [[8zly]] - SpPyK + fructose bisphosphate + oxalate + nucleotide