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New page: left|200px<br /> <applet load="2cuq" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cuq" /> '''Solution Structure of Second Lim Domain fro...
 
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[[Image:2cuq.gif|left|200px]]<br />
<applet load="2cuq" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2cuq" />
'''Solution Structure of Second Lim Domain from Human Skeletal Muscle Lim-Protein 2'''<br />


==Disease==
==Solution Structure of Second Lim Domain from Human Skeletal Muscle Lim-Protein 2==
Known disease associated with this structure: Hemophagocytic lymphohistiocytosis, familial, 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608897 608897]]
<StructureSection load='2cuq' size='340' side='right'caption='[[2cuq]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2cuq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CUQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cuq OCA], [https://pdbe.org/2cuq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cuq RCSB], [https://www.ebi.ac.uk/pdbsum/2cuq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cuq ProSAT], [https://www.topsan.org/Proteins/RSGI/2cuq TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FHL3_HUMAN FHL3_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/2cuq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cuq ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
2CUQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CUQ OCA].
*[[Muscle LIM protein|Muscle LIM protein]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Niraula, T.N.]]
[[Category: Niraula TN]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Saito K]]
[[Category: Saito, K.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: ZN]]
[[Category: four and a half lim domains 3]]
[[Category: lim domain]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
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Retrieved from "https://proteopedia.org/2cuq"