1zxj: Difference between revisions

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[[Image:1zxj.gif|left|200px]]


<!--
==Crystal structure of the hypthetical Mycoplasma protein, MPN555==
The line below this paragraph, containing "STRUCTURE_1zxj", creates the "Structure Box" on the page.
<StructureSection load='1zxj' size='340' side='right'caption='[[1zxj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1zxj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZXJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxj OCA], [https://pdbe.org/1zxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zxj RCSB], [https://www.ebi.ac.uk/pdbsum/1zxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxj ProSAT], [https://www.topsan.org/Proteins/BSGC/1zxj TOPSAN]</span></td></tr>
{{STRUCTURE_1zxj|  PDB=1zxj  |  SCENE= }}
</table>
 
== Function ==
'''Crystal structure of the hypthetical Mycoplasma protein, MPN555'''
[https://www.uniprot.org/uniprot/Y555_MYCPN Y555_MYCPN]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==Overview==
Check<jmol>
The crystal structure of the hypothetical protein MPN555 from Mycoplasma pneumoniae (gi|1673958) has been determined to a resolution of 2.8 Angstrom using anomalous diffraction data at the Se-peak wavelength. Structure determination revealed a mostly alpha-helical protein with a three-lobed shape. The three lobes or fingers delineate a central binding groove and additional grooves between lobes 1 and 3 and between lobes 2 and 3. For one of the molecules in the asymmetric unit, the central binding pocket was filled with a peptide from the uncleaved N-terminal affinity tag. The MPN555 structure has structural homology to two bacterial chaperone proteins: SurA and trigger factor from Escherichia coli. The structural data and the homology to other chaperone proteins suggests an involvement in protein folding as a molecular chaperone for MPN555.
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/1zxj_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1ZXJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXJ OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==Reference==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zxj ConSurf].
Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function., Schulze-Gahmen U, Aono S, Chen S, Yokota H, Kim R, Kim SH, Acta Crystallogr D Biol Crystallogr. 2005 Oct;61(Pt 10):1343-7. Epub 2005, Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16204885 16204885]
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Single protein]]
[[Category: Aono S]]
[[Category: Aono, S.]]
[[Category: Kim R]]
[[Category: BSGC, Berkeley Structural Genomics Center.]]
[[Category: Kim S-H]]
[[Category: Kim, R.]]
[[Category: Schulze-Gahmen U]]
[[Category: Kim, S H.]]
[[Category: Shengfeng C]]
[[Category: Schulze-Gahmen, U.]]
[[Category: Yokota H]]
[[Category: Shengfeng, C.]]
[[Category: Yokota, H.]]
[[Category: Berkeley structural genomics center]]
[[Category: Bsgc]]
[[Category: Mostly alpha helical protein]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Tri-lobal structure]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:12:18 2008''
Retrieved from "https://proteopedia.org/1zxj"