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[[Image:281d.gif|left|200px]]


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==CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)==
The line below this paragraph, containing "STRUCTURE_281d", creates the "Structure Box" on the page.
<StructureSection load='281d' size='340' side='right'caption='[[281d]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[281d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=281D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=281D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=281d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=281d OCA], [https://pdbe.org/281d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=281d RCSB], [https://www.ebi.ac.uk/pdbsum/281d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=281d ProSAT]</span></td></tr>
{{STRUCTURE_281d|  PDB=281d  |  SCENE= }}
</table>
 
__TOC__
'''CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)'''
</StructureSection>
 
[[Category: Large Structures]]
 
[[Category: Neidle S]]
==Overview==
[[Category: Nunn CM]]
The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC).
 
==About this Structure==
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=281D OCA].  
 
==Reference==
Structure of the A-DNA octamer d(GGCATGCC)., Nunn CM, Neidle S, Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299929 15299929]
[[Category: Neidle, S.]]
[[Category: Nunn, C M.]]
[[Category: A-dna]]
[[Category: Double helix]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:25:15 2008''
Retrieved from "https://proteopedia.org/281d"