2e72: Difference between revisions
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New page: left|200px<br /> <applet load="2e72" size="450" color="white" frame="true" align="right" spinBox="true" caption="2e72" /> '''Solution structure of the zinc finger domai... |
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== | ==Solution structure of the zinc finger domain of human KIAA0461== | ||
<StructureSection load='2e72' size='340' side='right'caption='[[2e72]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2e72]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E72 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e72 OCA], [https://pdbe.org/2e72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e72 RCSB], [https://www.ebi.ac.uk/pdbsum/2e72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e72 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e72 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/POGZ_HUMAN POGZ_HUMAN] Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.<ref>PMID:20562864</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Muto | [[Category: Muto Y]] | ||
[[Category: Shirouzu M]] | |||
[[Category: Shirouzu | [[Category: Suzuki S]] | ||
[[Category: Suzuki | [[Category: Tanabe W]] | ||
[[Category: Tanabe | [[Category: Terada T]] | ||
[[Category: Terada | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 16:34, 13 December 2023
Solution structure of the zinc finger domain of human KIAA0461
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