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New page: left|200px<br /> <applet load="2ebk" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ebk" /> '''Solution structure of the RWD domain of hum...
 
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[[Image:2ebk.gif|left|200px]]<br />
<applet load="2ebk" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2ebk" />
'''Solution structure of the RWD domain of human RWD domain containing protein 3'''<br />


==About this Structure==
==Solution structure of the RWD domain of human RWD domain containing protein 3==
2EBK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2EBK OCA].  
<StructureSection load='2ebk' size='340' side='right'caption='[[2ebk]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ebk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebk OCA], [https://pdbe.org/2ebk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebk RCSB], [https://www.ebi.ac.uk/pdbsum/2ebk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebk ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebk TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RWDD3_HUMAN RWDD3_HUMAN] Enhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination.<ref>PMID:17956732</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ebk ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Harada, T.]]
[[Category: Harada T]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Watabe S]]
[[Category: Watabe, S.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Yoneyama M]]
[[Category: Yoneyama, M.]]
[[Category: alpha+beta sandwich fold]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: rwd domain]]
[[Category: structural genomics]]
[[Category: unknown function]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 21:47:51 2007''
Retrieved from "https://proteopedia.org/2ebk"