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New page: left|200px<br /> <applet load="2edv" size="450" color="white" frame="true" align="right" spinBox="true" caption="2edv" /> '''Solution structure of the PDZ domain from h...
 
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[[Image:2edv.gif|left|200px]]<br />
<applet load="2edv" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2edv" />
'''Solution structure of the PDZ domain from human FERM and PDZ domain containing 1'''<br />


==About this Structure==
==Solution structure of the PDZ domain from human FERM and PDZ domain containing 1==
2EDV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2EDV OCA].  
<StructureSection load='2edv' size='340' side='right'caption='[[2edv]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2edv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EDV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2edv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edv OCA], [https://pdbe.org/2edv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2edv RCSB], [https://www.ebi.ac.uk/pdbsum/2edv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2edv ProSAT], [https://www.topsan.org/Proteins/RSGI/2edv TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FRPD1_HUMAN FRPD1_HUMAN] Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.<ref>PMID:18566450</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ed/2edv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2edv ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Kurosaki, C.]]
[[Category: Kurosaki C]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Seimiya K]]
[[Category: Seimiya, K.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Yoshida M]]
[[Category: Yoshida, M.]]
[[Category: cytoskeletal-associated protein]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: protein binding]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
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Retrieved from "https://proteopedia.org/2edv"