2b05: Difference between revisions

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[[Image:2b05.gif|left|200px]]


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==Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide==
The line below this paragraph, containing "STRUCTURE_2b05", creates the "Structure Box" on the page.
<StructureSection load='2b05' size='340' side='right'caption='[[2b05]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2b05]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B05 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
{{STRUCTURE_2b05| PDB=2b05 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b05 OCA], [https://pdbe.org/2b05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b05 RCSB], [https://www.ebi.ac.uk/pdbsum/2b05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b05 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/1433G_HUMAN 1433G_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:16511572</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/2b05_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b05 ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide'''
==See Also==
 
*[[14-3-3 protein 3D structures|14-3-3 protein 3D structures]]
 
== References ==
==About this Structure==
<references/>
2B05 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B05 OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith C]]
[[Category: Debreczeni, E J.]]
[[Category: Debreczeni EJ]]
[[Category: Delft, F von.]]
[[Category: Doyle D]]
[[Category: Doyle, D.]]
[[Category: Edwards A]]
[[Category: Edwards, A.]]
[[Category: Elkins J]]
[[Category: Elkins, J.]]
[[Category: Papagrigoriou E]]
[[Category: Papagrigoriou, E.]]
[[Category: Turnbull A]]
[[Category: Turnbull, A.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Yang X]]
[[Category: Yang, X.]]
[[Category: Zhao Y]]
[[Category: Zhao, Y.]]
[[Category: Von Delft F]]
[[Category: Cell cycle]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:41:17 2008''