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[[Image:2b7g.gif|left|200px]]


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==Structure of the Smaug Recognition RNA Element==
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<StructureSection load='2b7g' size='340' side='right'caption='[[2b7g]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2b7g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B7G FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b7g OCA], [https://pdbe.org/2b7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b7g RCSB], [https://www.ebi.ac.uk/pdbsum/2b7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b7g ProSAT]</span></td></tr>
{{STRUCTURE_2b7g| PDB=2b7g  |  SCENE= }}
</table>
 
<div style="background-color:#fffaf0;">
'''Structure of the Smaug Recognition RNA Element'''
== Publication Abstract from PubMed ==
 
 
==Overview==
The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.
The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.


==About this Structure==
RNA recognition by the Vts1p SAM domain.,Johnson PE, Donaldson LW Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:16429155<ref>PMID:16429155</ref>
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7G OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16429155 16429155]
</div>
[[Category: Donaldson, L W.]]
<div class="pdbe-citations 2b7g" style="background-color:#fffaf0;"></div>
[[Category: Johnson, P E.]]
== References ==
[[Category: Protein-rna complex]]
<references/>
[[Category: Rna]]
__TOC__
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:57:02 2008''
</StructureSection>
[[Category: Large Structures]]
[[Category: Donaldson LW]]
[[Category: Johnson PE]]

Latest revision as of 16:33, 13 December 2023

Structure of the Smaug Recognition RNA Element

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