2jp2: Difference between revisions
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New page: left|200px<br /> <applet load="2jp2" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jp2" /> '''Solution structure and resonance assignment... |
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== | ==Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2)== | ||
<StructureSection load='2jp2' size='340' side='right'caption='[[2jp2]]' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[2jp2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JP2 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp2 OCA], [https://pdbe.org/2jp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jp2 RCSB], [https://www.ebi.ac.uk/pdbsum/2jp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jp2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPRE2_HUMAN SPRE2_HUMAN] Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/2jp2_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jp2 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith C]] | ||
[[Category: Ball | [[Category: Ball LJ]] | ||
[[Category: Edwards | [[Category: Edwards A]] | ||
[[Category: Fossi | [[Category: Fossi M]] | ||
[[Category: Jarchau | [[Category: Jarchau T]] | ||
[[Category: Lemak | [[Category: Lemak A]] | ||
[[Category: Oschkinat | [[Category: Oschkinat H]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sundstrom | [[Category: Walter U]] | ||
[[Category: Walter | [[Category: Wiegelt J]] | ||
[[Category: Wiegelt | [[Category: Zimmermann J]] | ||
[[Category: Zimmermann | |||
