2jrf: Difference between revisions
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New page: left|200px<br /> <applet load="2jrf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jrf" /> '''Solution NMR structure of Tubulin polymeriz... |
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== | ==Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.== | ||
<StructureSection load='2jrf' size='340' side='right'caption='[[2jrf]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2jrf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JRF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jrf OCA], [https://pdbe.org/2jrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jrf RCSB], [https://www.ebi.ac.uk/pdbsum/2jrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jrf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TPPP3_HUMAN TPPP3_HUMAN] Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis.<ref>PMID:17105200</ref> <ref>PMID:19633818</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/2jrf_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jrf ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Acton | [[Category: Acton TB]] | ||
[[Category: Aramini | [[Category: Aramini JM]] | ||
[[Category: Baran | [[Category: Baran MC]] | ||
[[Category: Cunningham | [[Category: Cunningham K]] | ||
[[Category: Liu | [[Category: Liu J]] | ||
[[Category: Montelione | [[Category: Montelione GT]] | ||
[[Category: Nwosu C]] | |||
[[Category: Nwosu | [[Category: Rajan PK]] | ||
[[Category: Rajan | [[Category: Rossi P]] | ||
[[Category: Rossi | [[Category: Rost B]] | ||
[[Category: Rost | [[Category: Shastry R]] | ||
[[Category: Shastry | [[Category: Xiao R]] | ||
[[Category: Xiao | |||
Latest revision as of 10:11, 20 December 2023
Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.
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