2jrs: Difference between revisions

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New page: left|200px<br /> <applet load="2jrs" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jrs" /> '''Solution NMR Structure of CAPER RRM2 Domain...
 
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[[Image:2jrs.gif|left|200px]]<br />
<applet load="2jrs" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2jrs" />
'''Solution NMR Structure of CAPER RRM2 Domain. Northeast Structural Genomics Target HR4730A'''<br />


==About this Structure==
==Solution NMR Structure of CAPER RRM2 Domain. Northeast Structural Genomics Target HR4730A==
2JRS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JRS OCA].  
<StructureSection load='2jrs' size='340' side='right'caption='[[2jrs]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2jrs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JRS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jrs OCA], [https://pdbe.org/2jrs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jrs RCSB], [https://www.ebi.ac.uk/pdbsum/2jrs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jrs ProSAT], [https://www.topsan.org/Proteins/NESGC/2jrs TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RBM39_HUMAN RBM39_HUMAN] Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/2jrs_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jrs ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Acton, T.B.]]
[[Category: Acton TB]]
[[Category: Baran, M.C.]]
[[Category: Baran MC]]
[[Category: Cunningham, K.]]
[[Category: Cunningham K]]
[[Category: Liu, J.]]
[[Category: Liu J]]
[[Category: Montelione, G.T.]]
[[Category: Montelione GT]]
[[Category: NESG, Northeast.Structural.Genomics.Consortium.]]
[[Category: Nwosu C]]
[[Category: Nwosu, C.]]
[[Category: Owens L]]
[[Category: Owens, L.]]
[[Category: Rossi P]]
[[Category: Rossi, P.]]
[[Category: Rost B]]
[[Category: Rost, B.]]
[[Category: Swapna G]]
[[Category: Swapna, G.]]
[[Category: Xiao R]]
[[Category: Xiao, R.]]
[[Category: Zhao L]]
[[Category: Zhao, L.]]
[[Category: nesg]]
[[Category: northeast structural genomics consortium]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: rna binding motif of rbm39_human (caper)]]
[[Category: rna binding protein]]
[[Category: rrm2 domain]]
[[Category: solution nmr structure]]
[[Category: structural genomics]]
 
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