2o4x: Difference between revisions
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New page: left|200px<br /> <applet load="2o4x" size="450" color="white" frame="true" align="right" spinBox="true" caption="2o4x, resolution 2.00Å" /> '''Crystal structure o... |
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== | ==Crystal structure of human P100 tudor domain== | ||
<StructureSection load='2o4x' size='340' side='right'caption='[[2o4x]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2o4x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O4X FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4x OCA], [https://pdbe.org/2o4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o4x RCSB], [https://www.ebi.ac.uk/pdbsum/2o4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4x ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o4/2o4x_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o4x ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Cheng | [[Category: Cheng C]] | ||
[[Category: Liu | [[Category: Liu ZJ]] | ||
[[Category: Rao | [[Category: Rao Z]] | ||
[[Category: Shaw | [[Category: Shaw N]] | ||
[[Category: Silvennoinen | [[Category: Silvennoinen O]] | ||
[[Category: Wang | [[Category: Wang BC]] | ||
[[Category: Xu | [[Category: Xu H]] | ||
[[Category: Yang | [[Category: Yang J]] | ||
[[Category: Zhao | [[Category: Zhao M]] | ||
Latest revision as of 00:14, 28 December 2023
Crystal structure of human P100 tudor domain
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