2ob0: Difference between revisions

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New page: left|200px<br /> <applet load="2ob0" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ob0, resolution 1.80Å" /> '''Human MAK3 homolog ...
 
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[[Image:2ob0.gif|left|200px]]<br />
<applet load="2ob0" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2ob0, resolution 1.80&Aring;" />
'''Human MAK3 homolog in complex with Acetyl-CoA'''<br />


==About this Structure==
==Human MAK3 homolog in complex with Acetyl-CoA==
2OB0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with ACO as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Peptide_alpha-N-acetyltransferase Peptide alpha-N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.88 2.3.1.88] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2OB0 OCA].  
<StructureSection load='2ob0' size='340' side='right'caption='[[2ob0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ob0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OB0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ob0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ob0 OCA], [https://pdbe.org/2ob0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ob0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ob0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ob0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NAA50_HUMAN NAA50_HUMAN] Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity.<ref>PMID:16507339</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/2ob0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ob0 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptide alpha-N-acetyltransferase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Antoshenko T]]
[[Category: Antoshenko, T.]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith, C.H.]]
[[Category: Bernstein G]]
[[Category: Bernstein, G.]]
[[Category: Bochkarev A]]
[[Category: Bochkarev, A.]]
[[Category: Edwards AM]]
[[Category: Edwards, A.M.]]
[[Category: Loppnau P]]
[[Category: Loppnau, P.]]
[[Category: Plotnikov AN]]
[[Category: Plotnikov, A.N.]]
[[Category: Schuetz S]]
[[Category: SGC, Structural.Genomics.Consortium.]]
[[Category: Sundstrom M]]
[[Category: Schuetz, S.]]
[[Category: Walker JR]]
[[Category: Sundstrom, M.]]
[[Category: Weigelt J]]
[[Category: Walker, J.R.]]
[[Category: Wu H]]
[[Category: Weigelt, J.]]
[[Category: Wu, H.]]
[[Category: ACO]]
[[Category: acetyltransferase]]
[[Category: sgc]]
[[Category: structural genomics consortium]]
 
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Retrieved from "https://proteopedia.org/2ob0"