2pbc: Difference between revisions
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New page: left|200px<br /> <applet load="2pbc" size="450" color="white" frame="true" align="right" spinBox="true" caption="2pbc, resolution 1.80Å" /> '''FK506-binding prote... |
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== | ==FK506-binding protein 2== | ||
<StructureSection load='2pbc' size='340' side='right'caption='[[2pbc]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2pbc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbc OCA], [https://pdbe.org/2pbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbc RCSB], [https://www.ebi.ac.uk/pdbsum/2pbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FKBP2_HUMAN FKBP2_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbc_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pbc ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[FKBP 3D structures|FKBP 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | |||
[[Category: Arrowsmith | [[Category: Bochkarev A]] | ||
[[Category: Bochkarev | [[Category: Butler-Cole C]] | ||
[[Category: Butler-Cole | [[Category: Davis T]] | ||
[[Category: Davis | [[Category: Dhe-Paganon S]] | ||
[[Category: Dhe-Paganon | [[Category: Edwards AM]] | ||
[[Category: Edwards | [[Category: Neculai D]] | ||
[[Category: Neculai | [[Category: Sicheri F]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sicheri | [[Category: Walker JR]] | ||
[[Category: Sundstrom | [[Category: Weigelt J]] | ||
[[Category: Walker | |||
[[Category: Weigelt | |||
