2hsw: Difference between revisions
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< | ==Crystal structure of the uridine phosphorylase from Salmonella typhimurium in unliganded state at 1.99A resolution== | ||
<StructureSection load='2hsw' size='340' side='right'caption='[[2hsw]], [[Resolution|resolution]] 1.99Å' scene=''> | |||
== Structural highlights == | |||
or the | <table><tr><td colspan='2'>[[2hsw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HSW FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hsw OCA], [https://pdbe.org/2hsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hsw RCSB], [https://www.ebi.ac.uk/pdbsum/2hsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hsw ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hs/2hsw_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hsw ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]] | |||
__TOC__ | |||
== | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] | ||
[[Category: | [[Category: Dontsova MV]] | ||
[[Category: Gabdoulkhakov AG]] | |||
[[Category: Dontsova | [[Category: Mikhailov AM]] | ||
[[Category: Gabdoulkhakov | [[Category: Timofeev VI]] | ||
[[Category: Mikhailov | |||
[[Category: Timofeev | |||
Latest revision as of 09:34, 14 February 2024
Crystal structure of the uridine phosphorylase from Salmonella typhimurium in unliganded state at 1.99A resolution
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