2itb: Difference between revisions

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[[Image:2itb.gif|left|200px]]


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==CRYSTAL STRUCTURE OF A PUTATIVE TRNA-(MS(2)IO(6)A)-HYDROXYLASE (PP_2188) FROM PSEUDOMONAS PUTIDA KT2440 AT 2.05 A RESOLUTION==
The line below this paragraph, containing "STRUCTURE_2itb", creates the "Structure Box" on the page.
<StructureSection load='2itb' size='340' side='right'caption='[[2itb]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2itb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida_KT2440 Pseudomonas putida KT2440]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ITB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene></td></tr>
{{STRUCTURE_2itb|  PDB=2itb  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2itb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2itb OCA], [https://pdbe.org/2itb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2itb RCSB], [https://www.ebi.ac.uk/pdbsum/2itb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2itb ProSAT], [https://www.topsan.org/Proteins/JCSG/2itb TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of putative tRNA-(ms(2)io(6)a)-hydroxylase (NP_744337.1) from Pseudomonas Putida KT2440 at 2.05 A resolution'''
== Function ==
 
[https://www.uniprot.org/uniprot/MIAE_PSEPK MIAE_PSEPK] Involved in specific tRNA modification. Catalyzes the oxygen-dependent hydroxylation of 2-methylthio-N-6-isopentenyl adenosine (ms2i6A) to produce 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A) at position 37 in tRNAs.<ref>PMID:32785618</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2ITB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITB OCA].  
Check<jmol>
[[Category: Pseudomonas putida]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/2itb_consurf.spt"</scriptWhenChecked>
[[Category: JCSG, Joint Center for Structural Genomics.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Jcsg]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Joint center for structural genomic]]
  </jmolCheckbox>
[[Category: Np_744337 1]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2itb ConSurf].
[[Category: Protein structure initiative]]
<div style="clear:both"></div>
[[Category: Psi-2]]
== References ==
[[Category: Structural genomic]]
<references/>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 07:50:40 2008''
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas putida KT2440]]

Latest revision as of 07:40, 9 October 2024

CRYSTAL STRUCTURE OF A PUTATIVE TRNA-(MS(2)IO(6)A)-HYDROXYLASE (PP_2188) FROM PSEUDOMONAS PUTIDA KT2440 AT 2.05 A RESOLUTION

2itb, resolution 2.05Å

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