2jan: Difference between revisions

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[[Image:2jan.jpg|left|200px]]


<!--
==TYROSYL-TRNA SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS IN UNLIGANDED STATE==
The line below this paragraph, containing "STRUCTURE_2jan", creates the "Structure Box" on the page.
<StructureSection load='2jan' size='340' side='right'caption='[[2jan]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2jan]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JAN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jan OCA], [https://pdbe.org/2jan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jan RCSB], [https://www.ebi.ac.uk/pdbsum/2jan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jan ProSAT]</span></td></tr>
{{STRUCTURE_2jan| PDB=2jan |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYY_MYCTU SYY_MYCTU] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jan_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jan ConSurf].
<div style="clear:both"></div>


'''TYROSYL-TRNA SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS IN UNLIGANDED STATE'''
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2JAN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAN OCA].
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Single protein]]
[[Category: Bartunik HD]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Bourenkov GP]]
[[Category: Bartunik, H D.]]
[[Category: Hartmann MD]]
[[Category: Bourenkov, G P.]]
[[Category: Shkolnaya LA]]
[[Category: Hartmann, M D.]]
[[Category: Strizhov NI]]
[[Category: Shkolnaya, L A.]]
[[Category: Strizhov, N I.]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Aminoacylation]]
[[Category: Atp-binding]]
[[Category: Ligase]]
[[Category: Nucleotide-binding]]
[[Category: Protein biosynthesis]]
[[Category: Rna-binding]]
[[Category: Trna]]
[[Category: Tyrosine]]
[[Category: Tyrr]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 08:36:43 2008''

Latest revision as of 14:40, 13 December 2023

TYROSYL-TRNA SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS IN UNLIGANDED STATE

2jan, resolution 2.90Å

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