2jw5: Difference between revisions

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[[Image:2jw5.jpg|left|200px]]


<!--
==Polymerase Lambda BRCT domain==
The line below this paragraph, containing "STRUCTURE_2jw5", creates the "Structure Box" on the page.
<StructureSection load='2jw5' size='340' side='right'caption='[[2jw5]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2jw5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JW5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jw5 OCA], [https://pdbe.org/2jw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jw5 RCSB], [https://www.ebi.ac.uk/pdbsum/2jw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jw5 ProSAT]</span></td></tr>
{{STRUCTURE_2jw5| PDB=2jw5 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/2jw5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jw5 ConSurf].
<div style="clear:both"></div>


'''Polymerase Lambda BRCT domain'''
==See Also==
 
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
== References ==
==About this Structure==
<references/>
2JW5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JW5 OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: DeRose, E F.]]
[[Category: DeRose EF]]
[[Category: London, R E.]]
[[Category: London RE]]
[[Category: Moon, A F.]]
[[Category: Moon AF]]
[[Category: Mueller, G A.]]
[[Category: Mueller GA]]
[[Category: Pederson, L C.]]
[[Category: Pedersen LC]]
[[Category: Brct domain]]
[[Category: Dna damage]]
[[Category: Dna repair]]
[[Category: Dna replication]]
[[Category: Dna synthesis]]
[[Category: Dna-binding]]
[[Category: Dna-directed dna polymerase]]
[[Category: Family x polymerase]]
[[Category: Lyase]]
[[Category: Manganese]]
[[Category: Metal-binding]]
[[Category: Nucleotidyltransferase]]
[[Category: Nucleus]]
[[Category: Phosphorylation]]
[[Category: Polymorphism]]
[[Category: Protein binding]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:20:51 2008''
Retrieved from "https://proteopedia.org/2jw5"