2jx1: Difference between revisions
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==Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA== | |||
<StructureSection load='2jx1' size='340' side='right'caption='[[2jx1]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2jx1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JX1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jx1 OCA], [https://pdbe.org/2jx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jx1 RCSB], [https://www.ebi.ac.uk/pdbsum/2jx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jx1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MYT1_MOUSE MYT1_MOUSE] Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription (By similarity).<ref>PMID:9373037</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
== | Check<jmol> | ||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/2jx1_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jx1 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Gamsjaeger R]] | |||
[[Category: Gamsjaeger | [[Category: Kobus FJ]] | ||
[[Category: Kobus | [[Category: Kwan AH]] | ||
[[Category: Kwan | [[Category: Lehtomaki E]] | ||
[[Category: Lehtomaki | [[Category: Lowry JA]] | ||
[[Category: Lowry | [[Category: Mackay JP]] | ||
[[Category: Mackay | [[Category: Matthews JM]] | ||
[[Category: Matthews | [[Category: Swanton MK]] | ||
[[Category: Swanton | |||
Latest revision as of 19:06, 29 May 2024
Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA
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