2k1g: Difference between revisions

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[[Image:2k1g.jpg|left|200px]]


<!--
==Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162==
The line below this paragraph, containing "STRUCTURE_2k1g", creates the "Structure Box" on the page.
<StructureSection load='2k1g' size='340' side='right'caption='[[2k1g]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2k1g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jyx 2jyx]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K1G FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k1g OCA], [https://pdbe.org/2k1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k1g RCSB], [https://www.ebi.ac.uk/pdbsum/2k1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k1g ProSAT], [https://www.topsan.org/Proteins/NESGC/2k1g TOPSAN]</span></td></tr>
{{STRUCTURE_2k1g|  PDB=2k1g  |  SCENE= }}
</table>
 
== Function ==
'''Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162'''
[https://www.uniprot.org/uniprot/MEPS_ECOLI MEPS_ECOLI] A murein DD-endopeptidase with specificity for D-Ala-meso-diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Also has weak LD-carboxypeptidase activity on L-mDAP-D-Ala peptide bonds. Partially suppresses a prc disruption mutant.<ref>PMID:23062283</ref> <ref>PMID:9158724</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2K1G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jyx 2jyx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1G OCA].  
  <jmolCheckbox>
[[Category: Escherichia coli k12]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k1g_consurf.spt"</scriptWhenChecked>
[[Category: Single protein]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Acton, T B.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Aramini, J M.]]
  </jmolCheckbox>
[[Category: Baran, M C.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k1g ConSurf].
[[Category: Huang, Y J.]]
<div style="clear:both"></div>
[[Category: Jiang, M.]]
== References ==
[[Category: Liu, J.]]
<references/>
[[Category: Maglaqui, M.]]
__TOC__
[[Category: Montelione, G T.]]
</StructureSection>
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Escherichia coli K-12]]
[[Category: Rossi, P.]]
[[Category: Large Structures]]
[[Category: Rost, B.]]
[[Category: Acton TB]]
[[Category: Swapna, G V.T.]]
[[Category: Aramini JM]]
[[Category: Xiao, R.]]
[[Category: Baran MC]]
[[Category: Zhao, L.]]
[[Category: Huang YJ]]
[[Category: Bacterial lipoprotein]]
[[Category: Jiang M]]
[[Category: Construct optimized]]
[[Category: Liu J]]
[[Category: Cysteine peptidase]]
[[Category: Maglaqui M]]
[[Category: Membrane]]
[[Category: Montelione GT]]
[[Category: Nesg]]
[[Category: Rossi P]]
[[Category: Northeast structural genomics consortium]]
[[Category: Rost B]]
[[Category: Nplc/p60 family]]
[[Category: Swapna GVT]]
[[Category: Palmitate]]
[[Category: Xiao R]]
[[Category: Protein structure initiative]]
[[Category: Zhao L]]
[[Category: Psi-2]]
[[Category: Solution nmr structure]]
[[Category: Structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:27:57 2008''

Latest revision as of 06:43, 1 May 2024

Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162

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