2mhb: Difference between revisions

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[[Image:2mhb.gif|left|200px]]


<!--
==THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION==
The line below this paragraph, containing "STRUCTURE_2mhb", creates the "Structure Box" on the page.
<StructureSection load='2mhb' size='340' side='right'caption='[[2mhb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2mhb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MHB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
{{STRUCTURE_2mhb| PDB=2mhb |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mhb OCA], [https://pdbe.org/2mhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mhb RCSB], [https://www.ebi.ac.uk/pdbsum/2mhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mhb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE] Involved in oxygen transport from the lung to the various peripheral tissues.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/2mhb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2mhb ConSurf].
<div style="clear:both"></div>


'''THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION'''
==See Also==
 
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2MHB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1mhb 1mhb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHB OCA].
 
==Reference==
The structure of horse methaemoglobin at 2-0 A resolution., Ladner RC, Heidner EJ, Perutz MF, J Mol Biol. 1977 Aug 15;114(3):385-414. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/561852 561852]
[[Category: Equus caballus]]
[[Category: Equus caballus]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Heidner, E G.]]
[[Category: Heidner EG]]
[[Category: Ladner, R C.]]
[[Category: Ladner RC]]
[[Category: Perutz, M F.]]
[[Category: Perutz MF]]
[[Category: Oxygen transport]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:33:30 2008''

Latest revision as of 08:19, 13 August 2026

THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION

2mhb, resolution 2.00Å

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