2o18: Difference between revisions

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[[Image:2o18.gif|left|200px]]


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==Crystal structure of a Thiamine biosynthesis lipoprotein apbE, NorthEast Strcutural Genomics target ER559==
The line below this paragraph, containing "STRUCTURE_2o18", creates the "Structure Box" on the page.
<StructureSection load='2o18' size='340' side='right'caption='[[2o18]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2o18]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O18 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_2o18|  PDB=2o18  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o18 OCA], [https://pdbe.org/2o18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o18 RCSB], [https://www.ebi.ac.uk/pdbsum/2o18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o18 ProSAT], [https://www.topsan.org/Proteins/NESGC/2o18 TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of a Thiamine biosynthesis lipoprotein apbE, NorthEast Strcutural Genomics target ER559'''
== Function ==
 
[https://www.uniprot.org/uniprot/APBE_ECOLI APBE_ECOLI] Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine (HMP) moiety of thiamine (By similarity).
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2O18 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O18 OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o1/2o18_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o18 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Acton, T B.]]
[[Category: Acton TB]]
[[Category: Baran, M C.]]
[[Category: Baran MC]]
[[Category: Cunningham, K.]]
[[Category: Cunningham K]]
[[Category: Fang, Y.]]
[[Category: Fang Y]]
[[Category: Hunt, J F.]]
[[Category: Hunt JF]]
[[Category: Liu, J.]]
[[Category: Liu J]]
[[Category: Ma, L.]]
[[Category: Ma L]]
[[Category: Montelione, G T.]]
[[Category: Montelione GT]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Rost B]]
[[Category: Rost, B.]]
[[Category: Seetharaman J]]
[[Category: Seetharaman, J.]]
[[Category: Su M]]
[[Category: Su, M.]]
[[Category: Tong L]]
[[Category: Tong, L.]]
[[Category: Wang D]]
[[Category: Wang, D.]]
[[Category: Xiao R]]
[[Category: Xiao, R.]]
[[Category: Apbe]]
[[Category: Lipoprotein]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 10:10:41 2008''