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New page: left|200px<br /> <applet load="2yhx" size="450" color="white" frame="true" align="right" spinBox="true" caption="2yhx, resolution 2.1Å" /> '''SEQUENCING A PROTEIN...
 
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[[Image:2yhx.gif|left|200px]]<br />
<applet load="2yhx" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2yhx, resolution 2.1&Aring;" />
'''SEQUENCING A PROTEIN BY X-RAY CRYSTALLOGRAPHY. II. REFINEMENT OF YEAST HEXOKINASE B CO-ORDINATES AND SEQUENCE AT 2.1 ANGSTROMS RESOLUTION'''<br />


==About this Structure==
==SEQUENCING A PROTEIN BY X-RAY CRYSTALLOGRAPHY. II. REFINEMENT OF YEAST HEXOKINASE B CO-ORDINATES AND SEQUENCE AT 2.1 ANGSTROMS RESOLUTION==
2YHX is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with OTG as [http://en.wikipedia.org/wiki/ligand ligand]. This structure superseeds the now removed PDB entry 1YHX. The following page contains interesting information on the relation of 2YHX with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb50_1.html The Glycolytic Enzymes]]. Active as [http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2YHX OCA].  
<StructureSection load='2yhx' size='340' side='right'caption='[[2yhx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2yhx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1yhx 1yhx]. The February 2004 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''The Glycolytic Enzymes''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2004_2 10.2210/rcsb_pdb/mom_2004_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YHX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OTG:ORTHO-TOLUOYLGLUCOSAMINE'>OTG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yhx OCA], [https://pdbe.org/2yhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yhx RCSB], [https://www.ebi.ac.uk/pdbsum/2yhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yhx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HXKB_YEAST HXKB_YEAST] Main glucose phosphorylating enzyme. May play a regulatory role in both induction and repression of gene expression by glucose.


==Reference==
==See Also==
Sequencing a protein by x-ray crystallography. II. Refinement of yeast hexokinase B co-ordinates and sequence at 2.1 A resolution., Anderson CM, Stenkamp RE, Steitz TA, J Mol Biol. 1978 Jul 25;123(1):15-33. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=355643 355643]
*[[Hexokinase 3D structures|Hexokinase 3D structures]]
[[Category: Hexokinase]]
__TOC__
[[Category: Protein complex]]
</StructureSection>
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Saccharomyces cerevisiae]]
[[Category: The Glycolytic Enzymes]]
[[Category: The Glycolytic Enzymes]]
[[Category: Anderson, C.M.]]
[[Category: Anderson CM]]
[[Category: Steitz, T.A.]]
[[Category: Steitz TA]]
[[Category: Stenkamp, R.E.]]
[[Category: Stenkamp RE]]
[[Category: OTG]]
[[Category: alcohol acceptr)]]
[[Category: transferase(phosphoryl]]
 
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