2poy: Difference between revisions

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[[Image:2poy.jpg|left|200px]]


<!--
==Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A==
The line below this paragraph, containing "STRUCTURE_2poy", creates the "Structure Box" on the page.
<StructureSection load='2poy' size='340' side='right'caption='[[2poy]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2poy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II] and [https://en.wikipedia.org/wiki/Tolypocladium_inflatum Tolypocladium inflatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
{{STRUCTURE_2poy|  PDB=2poy  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2poy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poy OCA], [https://pdbe.org/2poy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2poy RCSB], [https://www.ebi.ac.uk/pdbsum/2poy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2poy ProSAT]</span></td></tr>
 
</table>
'''Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A'''
== Function ==
 
[https://www.uniprot.org/uniprot/A3FQA7_CRYPI A3FQA7_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2POY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POY OCA].  
Check<jmol>
[[Category: Cryptosporidium parvum iowa ii]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poy_consurf.spt"</scriptWhenChecked>
[[Category: Arrowsmith, C H.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Artz, J D.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Bochkarev, A.]]
  </jmolCheckbox>
[[Category: Edwards, A M.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2poy ConSurf].
[[Category: Hassanali, A.]]
<div style="clear:both"></div>
[[Category: Hills, T.]]
__TOC__
[[Category: Hui, R.]]
</StructureSection>
[[Category: Kozieradzki, I.]]
[[Category: Cryptosporidium parvum Iowa II]]
[[Category: Lew, J.]]
[[Category: Large Structures]]
[[Category: Lin, Y H.]]
[[Category: Tolypocladium inflatum]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Arrowsmith CH]]
[[Category: Schapira, M.]]
[[Category: Artz JD]]
[[Category: Sundstrom, M.]]
[[Category: Bochkarev A]]
[[Category: Weigelt, J.]]
[[Category: Edwards AM]]
[[Category: Wernimont, A K.]]
[[Category: Hassanali A]]
[[Category: Xiao, T.]]
[[Category: Hills T]]
[[Category: Zhao, Y.]]
[[Category: Hui R]]
[[Category: Cryptosporidium]]
[[Category: Kozieradzki I]]
[[Category: Cyclophilin]]
[[Category: Lew J]]
[[Category: Cyclosporin]]
[[Category: Lin YH]]
[[Category: Parvum]]
[[Category: Schapira M]]
[[Category: Sgc]]
[[Category: Sundstrom M]]
[[Category: Structural genomic]]
[[Category: Weigelt J]]
[[Category: Structural genomics consortium]]
[[Category: Wernimont AK]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 13:33:50 2008''
[[Category: Xiao T]]
[[Category: Zhao Y]]

Latest revision as of 11:06, 30 August 2023

Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A

2poy, resolution 1.80Å

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