2g2r: Difference between revisions

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New page: left|200px<br /> <applet load="2g2r" size="450" color="white" frame="true" align="right" spinBox="true" caption="2g2r, resolution 2.75Å" /> '''Green-fluorescent a...
 
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[[Image:2g2r.gif|left|200px]]<br />
<applet load="2g2r" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2g2r, resolution 2.75&Aring;" />
'''Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)'''<br />


==About this Structure==
==Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)==
2G2R is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with SO4 and TNS as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2G2R OCA].  
<StructureSection load='2g2r' size='340' side='right'caption='[[2g2r]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2g2r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G2R FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TNS:N-(TRANS-4-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC+ACID'>TNS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g2r OCA], [https://pdbe.org/2g2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g2r RCSB], [https://www.ebi.ac.uk/pdbsum/2g2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g2r ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HVM63_MOUSE HVM63_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/2g2r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g2r ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
The effects of antibodies on stilbene excited-state energetics., Tian F, Debler EW, Millar DP, Deniz AA, Wilson IA, Schultz PG, Angew Chem Int Ed Engl. 2006 Nov 27;45(46):7763-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17089439 17089439]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Debler EW]]
[[Category: Debler, E.W.]]
[[Category: Wilson IA]]
[[Category: Wilson, I.A.]]
[[Category: SO4]]
[[Category: TNS]]
[[Category: green-fluorescent antibody]]
[[Category: immunoglobulin]]
[[Category: stilbene-complex]]
 
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