2r3b: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2r3b.jpg|left|200px]]


<!--
==CRYSTAL STRUCTURE OF a ribokinase-like superfamily protein (EF1790) FROM ENTEROCOCCUS FAECALIS V583 AT 1.80 A RESOLUTION==
The line below this paragraph, containing "STRUCTURE_2r3b", creates the "Structure Box" on the page.
<StructureSection load='2r3b' size='340' side='right'caption='[[2r3b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2r3b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R3B FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_2r3b|  PDB=2r3b |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r3b OCA], [https://pdbe.org/2r3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r3b RCSB], [https://www.ebi.ac.uk/pdbsum/2r3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r3b ProSAT], [https://www.topsan.org/Proteins/JCSG/2r3b TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of a putative kinase in the ribokinase-like superfamily from Enterococcus faecalis V583 (NP_815490.1) at 1.80 A resolution'''
== Function ==
 
[https://www.uniprot.org/uniprot/NNRD_ENTFA NNRD_ENTFA] Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.[HAMAP-Rule:MF_01965]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2R3B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3B OCA].  
Check<jmol>
[[Category: Enterococcus faecalis v583]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r3/2r3b_consurf.spt"</scriptWhenChecked>
[[Category: JCSG, Joint Center for Structural Genomics.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Jcsg]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Joint center for structural genomic]]
  </jmolCheckbox>
[[Category: Np_815490 1]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r3b ConSurf].
[[Category: Protein structure initiative]]
<div style="clear:both"></div>
[[Category: Psi-2]]
__TOC__
[[Category: Putative kinase in the ribokinase-like superfamily from enterococcus faecalis v583]]
</StructureSection>
[[Category: Structural genomic]]
[[Category: Enterococcus faecalis V583]]
[[Category: Transferase]]
[[Category: Large Structures]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 16:09:56 2008''