2z68: Difference between revisions

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[[Image:2z68.jpg|left|200px]]


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==Crystal Structure Of An Artificial Metalloprotein: Cr[N-salicylidene-4-amino-3-hydroxyhydrocinnamic acid]/Wild Type Heme oxygenase==
The line below this paragraph, containing "STRUCTURE_2z68", creates the "Structure Box" on the page.
<StructureSection load='2z68' size='340' side='right'caption='[[2z68]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2z68]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z68 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2z68|  PDB=2z68  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z68 OCA], [https://pdbe.org/2z68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z68 RCSB], [https://www.ebi.ac.uk/pdbsum/2z68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z68 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q54AI1_CORDP Q54AI1_CORDP]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/2z68_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z68 ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We have succeeded in improving the stability of Fe(Schiff-base).heme oxygenase (HO) hybrids by ligand design based on the crystal structure of Fe(N,N'-bis(salicylidene)-3.4-diaminobenzene propionic acid).HO.


'''Crystal Structure Of An Artificial Metalloprotein: Cr[N-salicylidene-4-amino-3-hydroxyhydrocinnamic acid]/Wild Type Heme oxygenase'''
Ligand design for the improvement of stability of metal complex.protein hybrids.,Yokoi N, Ueno T, Unno M, Matsui T, Ikeda-Saito M, Watanabe Y Chem Commun (Camb). 2008 Jan 14;(2):229-31. doi: 10.1039/b713468a. Epub 2007 Oct , 24. PMID:18092096<ref>PMID:18092096</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2z68" style="background-color:#fffaf0;"></div>


==About this Structure==
==See Also==
2Z68 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z68 OCA].
*[[Heme oxygenase 3D structures|Heme oxygenase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Corynebacterium diphtheriae]]
[[Category: Corynebacterium diphtheriae]]
[[Category: Heme oxygenase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Ikeda-Saito M]]
[[Category: Ikeda-Saito, M.]]
[[Category: Ueno T]]
[[Category: Ueno, T.]]
[[Category: Unno M]]
[[Category: Unno, M.]]
[[Category: Watanabe Y]]
[[Category: Watanabe, Y.]]
[[Category: Yokoi N]]
[[Category: Yokoi, N.]]
[[Category: Artificial metalloprotein]]
[[Category: Electron-transfer]]
[[Category: Heme oxygenase]]
[[Category: Metal]]
[[Category: Oxidoreductase]]
[[Category: Salophen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 19:59:52 2008''