364d: Difference between revisions

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[[Image:364d.jpg|left|200px]]


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==3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA==
The line below this paragraph, containing "STRUCTURE_364d", creates the "Structure Box" on the page.
<StructureSection load='364d' size='340' side='right'caption='[[364d]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[364d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=356d 356d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=364D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=364D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1SC:5-O-THIOPHOSPHONOCYTIDINE'>1SC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_364d|  PDB=364d  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=364d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=364d OCA], [https://pdbe.org/364d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=364d RCSB], [https://www.ebi.ac.uk/pdbsum/364d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=364d ProSAT]</span></td></tr>
 
</table>
'''3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA'''
__TOC__
 
</StructureSection>
 
[[Category: Escherichia coli]]
==Overview==
[[Category: Large Structures]]
Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been determined at 3.0 and 1.5 A, respectively. This loop E region is distorted by three "cross-strand purine stacks" and three novel, water-mediated noncanonical base pairs and stabilized by a four metal ion zipper. These features give its minor groove a unique hydrogen-bonding surface and make the adjacent major groove wide enough to permit recognition by the ribosomal protein L25, which is expected to bind to this surface.
[[Category: Correll CC]]
 
[[Category: Freeborn B]]
==About this Structure==
[[Category: Moore PB]]
This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=356d 356d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=364D OCA].  
[[Category: Steitz TA]]
 
==Reference==
Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9393863 9393863]
[[Category: Correll, C C.]]
[[Category: Freeborn, B.]]
[[Category: Moore, P B.]]
[[Category: Steitz, T A.]]
[[Category: Double helix]]
[[Category: Internal loop]]
[[Category: Kinked]]
[[Category: Mismatched]]
[[Category: Modified]]
[[Category: Overhanging base]]
[[Category: U-rna]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 20:17:24 2008''
Retrieved from "https://proteopedia.org/364d"