4ait: Difference between revisions

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[[Image:4ait.gif|left|200px]]


<!--
==RESTRAINED ENERGY REFINEMENT WITH TWO DIFFERENT ALGORITHMS AND FORCE FIELDS OF THE STRUCTURE OF THE ALPHA-AMYLASE INHIBITOR TENDAMISTAT DETERMINED BY NMR IN SOLUTION==
The line below this paragraph, containing "STRUCTURE_4ait", creates the "Structure Box" on the page.
<StructureSection load='4ait' size='340' side='right'caption='[[4ait]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4ait]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AIT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 1 model</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ait FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ait OCA], [https://pdbe.org/4ait PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ait RCSB], [https://www.ebi.ac.uk/pdbsum/4ait PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ait ProSAT]</span></td></tr>
{{STRUCTURE_4ait|  PDB=4ait  |  SCENE= }}
</table>
 
== Function ==
'''RESTRAINED ENERGY REFINEMENT WITH TWO DIFFERENT ALGORITHMS AND FORCE FIELDS OF THE STRUCTURE OF THE ALPHA-AMYLASE INHIBITOR TENDAMISTAT DETERMINED BY NMR IN SOLUTION'''
[https://www.uniprot.org/uniprot/IAA_STRTE IAA_STRTE] Inhibits mammalian alpha-amylases specifically but has no action on plant and microbial alpha-amylases. Forms a tight stoichiometric 1:1 complex with alpha-amylase.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
4AIT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AIT OCA].  
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ai/4ait_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4ait ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces tendae]]
[[Category: Streptomyces tendae]]
[[Category: Billeter, M.]]
[[Category: Billeter M]]
[[Category: Braun, W.]]
[[Category: Braun W]]
[[Category: Schaumann, T.]]
[[Category: Schaumann T]]
[[Category: Wuthrich, K.]]
[[Category: Wuthrich K]]
[[Category: Alpha-amylase inhibitor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 22:20:26 2008''
Retrieved from "https://proteopedia.org/4ait"