1bkl: Difference between revisions

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New page: left|200px<br /><applet load="1bkl" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bkl, resolution 2.1Å" /> '''SELF-ASSOCIATED APO S...
 
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[[Image:1bkl.jpg|left|200px]]<br /><applet load="1bkl" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1bkl, resolution 2.1&Aring;" />
'''SELF-ASSOCIATED APO SRC SH2 DOMAIN'''<br />


==About this Structure==
==SELF-ASSOCIATED APO SRC SH2 DOMAIN==
1BKL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BKL OCA].  
<StructureSection load='1bkl' size='340' side='right'caption='[[1bkl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1bkl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BKL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bkl OCA], [https://pdbe.org/1bkl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bkl RCSB], [https://www.ebi.ac.uk/pdbsum/1bkl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bkl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRC_RSVSA SRC_RSVSA] This phosphoprotein, required for both the initiation and the maintenance of neoplastic transformation, is a protein kinase that catalyzes the phosphorylation of tyrosine residues in vitro.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/1bkl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bkl ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rous sarcoma virus]]
[[Category: Rous sarcoma virus]]
[[Category: Single protein]]
[[Category: Holland DR]]
[[Category: Transferase]]
[[Category: Rubin JR]]
[[Category: Holland, D.R.]]
[[Category: Rubin, J.R.]]
[[Category: phosphotyrosine recognition domain]]
[[Category: pp60 src sh2 domain]]
[[Category: v-src sh2 domain]]
 
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