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New page: left|200px<br /><applet load="1bp2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bp2, resolution 1.7Å" /> '''STRUCTURE OF BOVINE P...
 
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[[Image:1bp2.gif|left|200px]]<br /><applet load="1bp2" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1bp2, resolution 1.7&Aring;" />
'''STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2 AT 1.7 ANGSTROMS RESOLUTION'''<br />


==About this Structure==
==STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2 AT 1.7 ANGSTROMS RESOLUTION==
1BP2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with CA and MPD as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BP2 OCA].  
<StructureSection load='1bp2' size='340' side='right'caption='[[1bp2]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1bp2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BP2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bp2 OCA], [https://pdbe.org/1bp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bp2 RCSB], [https://www.ebi.ac.uk/pdbsum/1bp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bp2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PA21B_BOVIN PA21B_BOVIN] PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/1bp2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bp2 ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Structure of bovine pancreatic phospholipase A2 at 1.7A resolution., Dijkstra BW, Kalk KH, Hol WG, Drenth J, J Mol Biol. 1981 Mar 25;147(1):97-123. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7265241 7265241]
*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Phospholipase A(2)]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Dijkstra BW]]
[[Category: Dijkstra, B.W.]]
[[Category: Drenth J]]
[[Category: Drenth, J.]]
[[Category: Hol WGJ]]
[[Category: Hol, W.G.J.]]
[[Category: Kalk KH]]
[[Category: Kalk, K.H.]]
[[Category: CA]]
[[Category: MPD]]
[[Category: hydrolase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 11:48:26 2007''
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