2jx4: Difference between revisions

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New page: '''Unreleased structure''' The entry 2jx4 is ON HOLD until Paper Publication Authors: Bellot, G., Demene, H. Description: NMR structure of the intracellular loop (i3) of the vasopressi...
 
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'''Unreleased structure'''


The entry 2jx4 is ON HOLD  until Paper Publication
==NMR structure of the intracellular loop (i3) of the vasopressin V2 receptor (GPCR)==
 
<StructureSection load='2jx4' size='340' side='right'caption='[[2jx4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
Authors: Bellot, G., Demene, H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2jx4]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JX4 FirstGlance]. <br>
Description: NMR structure of the intracellular loop (i3) of the vasopressin V2 receptor (GPCR)
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCS:CARBOXYMETHYLATED+CYSTEINE'>CCS</scene>, <scene name='pdbligand=DGN:D-GLUTAMINE'>DGN</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 08:32:42 2008''
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jx4 OCA], [https://pdbe.org/2jx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jx4 RCSB], [https://www.ebi.ac.uk/pdbsum/2jx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jx4 ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/V2R_RAT V2R_RAT]] Involved in renal water reabsorption (By similarity). Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/2jx4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jx4 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Bellot, G]]
[[Category: Demene, H]]
[[Category: G-protein coupled receptor]]
[[Category: Glycoprotein]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Palmitate]]
[[Category: Phosphorylation]]
[[Category: Protein]]
[[Category: Receptor]]
[[Category: Transducer]]
[[Category: Transmembrane]]