2jyb: Difference between revisions
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New page: '''Unreleased structure''' The entry 2jyb is ON HOLD until Paper Publication Authors: Boroujerdi, A.A.F.B., Young, J.K. Description: binary hvDHFR1:folate complex ''Page seeded by [htt... |
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==binary hvDHFR1:folate complex== | |||
<StructureSection load='2jyb' size='340' side='right'caption='[[2jyb]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2jyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloferax_volcanii Haloferax volcanii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JYB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jyb OCA], [https://pdbe.org/2jyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jyb RCSB], [https://www.ebi.ac.uk/pdbsum/2jyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jyb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DYRA_HALVD DYRA_HALVD] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.<ref>PMID:2509470</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jy/2jyb_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jyb ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Haloferax volcanii]] | |||
[[Category: Large Structures]] | |||
[[Category: Boroujerdi AAFB]] | |||
[[Category: Young JK]] | |||
Latest revision as of 06:43, 1 May 2024
binary hvDHFR1:folate complex
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