2qnb: Difference between revisions
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New page: '''Unreleased structure''' The entry 2qnb is ON HOLD until Paper Publication Authors: Chrysina, E.D., Tiraidis, C., Alexacou, K.-M., Zographos, S.E., Leonidas, D.D., Oikonomakos, N.G. ... |
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==Glycogen Phosphorylase b in complex with N-benzoyl-N'-beta-D-glucopyranosyl urea== | |||
<StructureSection load='2qnb' size='340' side='right'caption='[[2qnb]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2qnb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QNB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QNB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BZD:N-BENZOYL-N-BETA-D-GLUCOPYRANOSYL+UREA'>BZD</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qnb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qnb OCA], [https://pdbe.org/2qnb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qnb RCSB], [https://www.ebi.ac.uk/pdbsum/2qnb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qnb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/2qnb_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qnb ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Glycogen phosphorylase 3D structures|Glycogen phosphorylase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Alexacou K-M]] | |||
[[Category: Chrysina ED]] | |||
[[Category: Leonidas DD]] | |||
[[Category: Oikonomakos NG]] | |||
[[Category: Tiraidis C]] | |||
[[Category: Zographos SE]] | |||
Latest revision as of 11:36, 30 August 2023
Glycogen Phosphorylase b in complex with N-benzoyl-N'-beta-D-glucopyranosyl urea
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