2v9z: Difference between revisions
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New page: '''Unreleased structure''' The entry 2v9z is ON HOLD until Paper Publication Authors: Koudelakova, T., Prokop, Z., Sato, Y., Lapkouski, M., Chovancova, E., Monincova, M., Jesenska, A., ... |
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==Structure of the Rhodococcus haloalkane dehalogenase mutant with enhanced enantioselectivity== | |||
<StructureSection load='2v9z' size='340' side='right'caption='[[2v9z]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2v9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9Z FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9z OCA], [https://pdbe.org/2v9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9z RCSB], [https://www.ebi.ac.uk/pdbsum/2v9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9z ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v9z_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v9z ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rhodococcus rhodochrous]] | |||
[[Category: Chovancova E]] | |||
[[Category: Damborsky J]] | |||
[[Category: Emmer J]] | |||
[[Category: Jesenska A]] | |||
[[Category: Koudelakova T]] | |||
[[Category: Kuta Smatanova I]] | |||
[[Category: Lapkouski M]] | |||
[[Category: Monincova M]] | |||
[[Category: Nagata Y]] | |||
[[Category: Prokop Z]] | |||
[[Category: Sato Y]] | |||
[[Category: Senda T]] | |||
Latest revision as of 15:11, 13 December 2023
Structure of the Rhodococcus haloalkane dehalogenase mutant with enhanced enantioselectivity
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