3b3l: Difference between revisions

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New page: '''Unreleased structure''' The entry 3b3l is ON HOLD until Paper Publication Authors: Trinh, C.H., Asipu, A., Bonthron, D.T., Phillips, S.E.V. Description: Crystal structures of altern...
 
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'''Unreleased structure'''


The entry 3b3l is ON HOLD  until Paper Publication
==Crystal structures of alternatively-spliced isoforms of human ketohexokinase==
<StructureSection load='3b3l' size='340' side='right'caption='[[3b3l]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3b3l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B3L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b3l OCA], [https://pdbe.org/3b3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b3l RCSB], [https://www.ebi.ac.uk/pdbsum/3b3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b3l ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN] Defects in KHK are the cause of fructosuria (FRUCT) [MIM:[https://omim.org/entry/229800 229800]. Benign defect of intermediary metabolism.<ref>PMID:19237742</ref> <ref>PMID:7833921</ref>
== Function ==
[https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/3b3l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b3l ConSurf].
<div style="clear:both"></div>


Authors: Trinh, C.H., Asipu, A., Bonthron, D.T., Phillips, S.E.V.
==See Also==
 
*[[Ketohexokinase|Ketohexokinase]]
Description: Crystal structures of alternatively-spliced isoforms of human ketohexokinase
== References ==
 
<references/>
 
__TOC__
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:23:42 2008''
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Asipu A]]
[[Category: Bonthron DT]]
[[Category: Phillips SEV]]
[[Category: Trinh CH]]
Retrieved from "https://proteopedia.org/3b3l"