3cl3: Difference between revisions
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New page: '''Unreleased structure''' The entry 3cl3 is ON HOLD until Paper Publication Authors: Bagneris, C., Ageichik, A.V., Cronin, N., Boshoff, C., Waksman, G., Barrett, T. Description: Cryst... |
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==Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome== | |||
<StructureSection load='3cl3' size='340' side='right'caption='[[3cl3]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3cl3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CL3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cl3 OCA], [https://pdbe.org/3cl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cl3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cl3 ProSAT]</span></td></tr> | |||
</table> | |||
'' | == Function == | ||
[https://www.uniprot.org/uniprot/Q76RF1_HHV8 Q76RF1_HHV8] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/3cl3_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cl3 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Human gammaherpesvirus 8]] | |||
[[Category: Large Structures]] | |||
[[Category: Ageichik AV]] | |||
[[Category: Bagneris C]] | |||
[[Category: Barrett T]] | |||
[[Category: Boshoff C]] | |||
[[Category: Cronin N]] | |||
[[Category: Waksman G]] | |||
Latest revision as of 09:36, 21 February 2024
Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome
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