3d0t: Difference between revisions
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New page: '''Unreleased structure''' The entry 3d0t is ON HOLD until Paper Publication Authors: Xu, Z., Nix, J.C., Devlin, K., Misra, S. Description: Crystal structure of Cochaperone ''Page se... |
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==Structure of the BNB domain of the Hsp70 cochaperone Bag2== | |||
<StructureSection load='3d0t' size='340' side='right'caption='[[3d0t]], [[Resolution|resolution]] 2.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3d0t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D0T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d0t OCA], [https://pdbe.org/3d0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d0t RCSB], [https://www.ebi.ac.uk/pdbsum/3d0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d0t ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BAG2_MOUSE BAG2_MOUSE] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d0/3d0t_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d0t ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[BAG family proteins 3D structures|BAG family proteins 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Devlin K]] | |||
[[Category: Misra S]] | |||
[[Category: Nix JC]] | |||
[[Category: Xu Z]] | |||
Latest revision as of 09:39, 21 February 2024
Structure of the BNB domain of the Hsp70 cochaperone Bag2
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