3d4p: Difference between revisions

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New page: '''Unreleased structure''' The entry 3d4p is ON HOLD Authors: Schramm, V.L., Almo, S.C., Gutierrez, J.A., Ho, M. Description: Crystal structure of Lactate Dehydrogenase from Staphyloco...
 
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'''Unreleased structure'''


The entry 3d4p is ON HOLD
==Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate==
<StructureSection load='3d4p' size='340' side='right'caption='[[3d4p]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3d4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D4P FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d4p OCA], [https://pdbe.org/3d4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d4p RCSB], [https://www.ebi.ac.uk/pdbsum/3d4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d4p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/3d4p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d4p ConSurf].
<div style="clear:both"></div>


Authors: Schramm, V.L., Almo, S.C., Gutierrez, J.A., Ho, M.
==See Also==
 
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
Description: Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate
== References ==
 
<references/>
 
__TOC__
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:37:06 2008''
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus COL]]
[[Category: Almo SC]]
[[Category: Gutierrez JA]]
[[Category: Ho M]]
[[Category: Schramm VL]]
Retrieved from "https://proteopedia.org/3d4p"