2zof: Difference between revisions

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[[Image:2zof.jpg|left|200px]]


<!--
==Crystal structure of mouse carnosinase CN2 complexed with MN and bestatin==
The line below this paragraph, containing "STRUCTURE_2zof", creates the "Structure Box" on the page.
<StructureSection load='2zof' size='340' side='right'caption='[[2zof]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2zof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZOF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BES:2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC+ACID'>BES</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
{{STRUCTURE_2zof|  PDB=2zof  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zof OCA], [https://pdbe.org/2zof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zof RCSB], [https://www.ebi.ac.uk/pdbsum/2zof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zof ProSAT]</span></td></tr>
 
</table>
'''Crystal structure of mouse carnosinase CN2 complexed with MN and bestatin'''
== Function ==
 
[https://www.uniprot.org/uniprot/CNDP2_MOUSE CNDP2_MOUSE] Hydrolyzes a variety of dipeptides including L-carnosine. Has a strong preference for Cys-Gly (By similarity).
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2ZOF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOF OCA].  
Check<jmol>
[[Category: Cytosol nonspecific dipeptidase]]
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/2zof_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zof ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Kusunoki M]]
[[Category: Kusunoki, M.]]
[[Category: Okumura N]]
[[Category: Okumura, N.]]
[[Category: Unno H]]
[[Category: Unno, H.]]
[[Category: Yamashita T]]
[[Category: Yamashita, T.]]
[[Category: Bestatin]]
[[Category: Carboxypeptidase]]
[[Category: Carnosinase]]
[[Category: Cn2]]
[[Category: Cndp dipeptidase 2]]
[[Category: Cndp2]]
[[Category: Hydrolase]]
[[Category: L-carnosine]]
[[Category: Metal-binding]]
[[Category: Metallopeptidase]]
[[Category: Metalloprotease]]
[[Category: Mn]]
[[Category: Protease]]
[[Category: Protein-inhibitor complex]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 10:46:09 2008''
Retrieved from "https://proteopedia.org/2zof"